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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
55484

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:55484

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:55484
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0051393alpha-actinin bindingCACNA1CIPIUniProtKB:P35609HumanPMID:17110593
Molecular FunctionGO:0005516calmodulin bindingCACNA1CIPIUniProtKB:P62158HumanPMID:15140941
Molecular FunctionGO:0019899enzyme bindingCacna1cIPIUniProtKB:B1AWC9|UniProtKB:Q01063MouseMGI:MGI:5286798|PMID:21670503
Molecular FunctionGO:0008331high voltage-gated calcium channel activityCacna1cIMPRatRGD:7205456|PMID:19422800
Molecular FunctionGO:0008331high voltage-gated calcium channel activityCacna1cIDARatRGD:7205477|PMID:17068255
Molecular FunctionGO:0044325ion channel bindingCacna1cIPIUniProtKB:F1PEE8RatPMID:11576544
Molecular FunctionGO:0044325ion channel bindingCacna1cIPIUniProtKB:P11716RatPMID:11576544
Molecular FunctionGO:0044325ion channel bindingCacna1cIPIUniProtKB:F1PEE8RatPMID:11576544
Molecular FunctionGO:0044325ion channel bindingCacna1cIPIUniProtKB:P11716RatPMID:11576544
Molecular FunctionGO:0005515protein bindingCACNA1CIPIUniProtKB:Q86UR5HumanPMID:11438518
Molecular FunctionGO:0005515protein bindingCACNA1CIPIUniProtKB:P62158HumanPMID:15140941
Molecular FunctionGO:0005515protein bindingCACNA1CIPIUniProtKB:Q9NZU7HumanPMID:15140941
Molecular FunctionGO:0005515protein bindingCACNA1CIPIUniProtKB:P62158HumanPMID:20953164
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:Q62174MouseMGI:MGI:3614746|PMID:16352659
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:Q8CC27MouseMGI:MGI:3652477|PMID:16787652
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:Q9Z0F4MouseMGI:MGI:4821678|PMID:20639889
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:Q9WUD9RatPMID:16352297
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:P63329RatPMID:19478199
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:Q92905RatRGD:1580158|PMID:16483597
Molecular FunctionGO:0005515protein bindingCacna1cIPIRGD:620385RatRGD:7207146|PMID:17224447
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:O88751RatRGD:7207149|PMID:15140941
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:O88751RatPMID:15140941
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:Q9WUD9RatPMID:16352297
Molecular FunctionGO:0005515protein bindingCacna1cIPIUniProtKB:P63329RatPMID:19478199
Molecular FunctionGO:0019904protein domain specific bindingCacna1cIPIRGD:1303071RatRGD:1304018|PMID:14569017
Molecular FunctionGO:0051721protein phosphatase 2A bindingCacna1cIPIRGD:3380RatRGD:1582610|PMID:16519540
Molecular FunctionGO:0051721protein phosphatase 2A bindingCacna1cIPIRGD:3381RatRGD:1582610|PMID:16519540
Molecular FunctionGO:0005245voltage-gated calcium channel activityCACNA1CIDAHumanPMID:12130699
Molecular FunctionGO:0005245voltage-gated calcium channel activityCACNA1CIDAHumanPMID:8392192
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIDAMouseMGI:MGI:51674|PMID:1385406
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIDAMouseMGI:MGI:70188|PMID:7814415
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIDAMouseMGI:MGI:76166|PMID:7635187
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIMPMGI:MGI:2674119|MGI:MGI:2176227MouseMGI:MGI:2670808|PMID:12881419
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIMPMGI:MGI:3047071MouseMGI:MGI:3513486|PMID:15504730
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIMPMGI:MGI:2674114MouseMGI:MGI:3607037|PMID:16251435
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIDAMouseMGI:MGI:3607433|PMID:16267232
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIMPMGI:MGI:2674119|MGI:MGI:2389040MouseMGI:MGI:3663939|PMID:14609949
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIMPRatRGD:1580158|PMID:16483597
Molecular FunctionGO:0005245voltage-gated calcium channel activityCacna1cIDARatRGD:1582591|PMID:16554304
Cellular ComponentGO:0002095caveolar macromolecular signaling complexCacna1cIDAMouseMGI:MGI:3628972|PMID:16648270
Cellular ComponentGO:0005623cellCacna1cIMPMGI:MGI:2674119|MGI:MGI:2176227MouseMGI:MGI:2670808|PMID:12881419
Cellular ComponentGO:0005737cytoplasmCACNA1CIDAHumanPMID:11206130
Cellular ComponentGO:0030425dendriteCacna1cIDARatRGD:7207146|PMID:17224447
Cellular ComponentGO:0030425dendriteCacna1cIDARatRGD:7207149|PMID:15140941
Cellular ComponentGO:0030425dendriteCacna1cIDARatPMID:15140941
Cellular ComponentGO:0043198dendritic shaftCacna1cIDAMouseMGI:MGI:3580191|PMID:15090038
Cellular ComponentGO:0016021integral component of membraneCACNA1CIDAHumanPMID:8392192
Cellular ComponentGO:0016020membraneCacna1cIDAMouseMGI:MGI:3699638|PMID:15132976
Cellular ComponentGO:0016020membraneCacna1cIDARatRGD:1582610|PMID:16519540
Cellular ComponentGO:0043025neuronal cell bodyCacna1cIDAMouseMGI:MGI:3580191|PMID:15090038
Cellular ComponentGO:0043025neuronal cell bodyCacna1cIDARatRGD:7207146|PMID:17224447
Cellular ComponentGO:0043025neuronal cell bodyCacna1cIDARatRGD:7207149|PMID:15140941
Cellular ComponentGO:0043025neuronal cell bodyCacna1cIDARatPMID:15140941
Cellular ComponentGO:0005634nucleusCacna1cIDARatRGD:7207149|PMID:15140941
Cellular ComponentGO:0005886plasma membraneCACNA1CIDAHumanPMID:11206130
Cellular ComponentGO:0005886plasma membraneCacna1cIDAMouseMGI:MGI:73956|PMID:7598723
Cellular ComponentGO:0005886plasma membraneCacna1cIDAMouseMGI:MGI:3580191|PMID:15090038
Cellular ComponentGO:0005886plasma membraneCacna1cIDARatRGD:7205477|PMID:17068255
Cellular ComponentGO:0014069postsynaptic densityCACNA1CIDAHumanPMID:14140941
Cellular ComponentGO:0014069postsynaptic densityCacna1cIDARatRGD:7207149|PMID:15140941
Cellular ComponentGO:0014069postsynaptic densityCacna1cIDARatPMID:15140941
Cellular ComponentGO:0042734presynaptic membraneCacna1cIDARatRGD:7207149|PMID:15140941
Cellular ComponentGO:0043234protein complexCacna1cIDARatRGD:7205477|PMID:17068255
Cellular ComponentGO:0043234protein complexCacna1cIDARatRGD:7207146|PMID:17224447
Cellular ComponentGO:0042383sarcolemmaCacna1cIDARatRGD:1580158|PMID:16483597
Cellular ComponentGO:0042383sarcolemmaCacna1cIDARatRGD:7175530|PMID:21474431
Cellular ComponentGO:0030315T-tubuleCacna1cIDARatRGD:1304018|PMID:14569017
Cellular ComponentGO:0005891voltage-gated calcium channel complexCACNA1CIDAHumanPMID:12130699
Cellular ComponentGO:0005891voltage-gated calcium channel complexCacna1cIDARatRGD:1582591|PMID:16554304
Cellular ComponentGO:0030018Z discCacna1cIDAMouseMGI:MGI:3849347|PMID:19383796
Cellular ComponentGO:0030018Z discCacna1cIDARatRGD:1600288|PMID:15980179
Cellular ComponentGO:0030018Z discCacna1cIDARatPMID:11053140
Cellular ComponentGO:0030018Z discCacna1cIDARatPMID:11053140
Biological ProcessGO:0007628adult walking behaviorCacna1cIGIMGI:MGI:109482MouseMGI:MGI:1329569|PMID:9882694
Biological ProcessGO:0070509calcium ion importCacna1cIMPRatRGD:7205456|PMID:19422800
Biological ProcessGO:0070588calcium ion transmembrane transportCacna1cIMPMGI:MGI:2674119|MGI:MGI:2176227MouseMGI:MGI:2670808|PMID:12881419
Biological ProcessGO:0006816calcium ion transportCacna1cIDAMouseMGI:MGI:76166|PMID:7635187
Biological ProcessGO:0006816calcium ion transportCacna1cIMPMGI:MGI:2674114MouseMGI:MGI:3607037|PMID:16251435
Biological ProcessGO:0006816calcium ion transportCacna1cIMPMGI:MGI:2674119MouseMGI:MGI:3699638|PMID:15132976
Biological ProcessGO:0006816calcium ion transportCacna1cIMPRatRGD:1580158|PMID:16483597
Biological ProcessGO:0017156calcium ion-dependent exocytosisCacna1cIMPMGI:MGI:2674119|MGI:MGI:2176227MouseMGI:MGI:2670808|PMID:12881419
Biological ProcessGO:0006874cellular calcium ion homeostasisCacna1cIMPMGI:MGI:2674119MouseMGI:MGI:3699638|PMID:15132976
Biological ProcessGO:0042593glucose homeostasisCacna1cIMPMGI:MGI:2674119|MGI:MGI:2176227MouseMGI:MGI:2670808|PMID:12881419
Biological ProcessGO:0030252growth hormone secretionCacna1cIDAMouseMGI:MGI:51674|PMID:1385406
Biological ProcessGO:0030073insulin secretionCacna1cIMPMGI:MGI:2674119|MGI:MGI:2176227MouseMGI:MGI:2670808|PMID:12881419
Biological ProcessGO:0007204positive regulation of cytosolic calcium ion concentrationCACNA1CIDAHumanPMID:12130699
Biological ProcessGO:0008217regulation of blood pressureCacna1cIMPMGI:MGI:2674119|MGI:MGI:2389040MouseMGI:MGI:3663939|PMID:14609949
Biological ProcessGO:0034765regulation of ion transmembrane transportCacna1cIMPMGI:MGI:2674119|MGI:MGI:2176227MouseMGI:MGI:2670808|PMID:12881419
Biological ProcessGO:0046620regulation of organ growthCacna1cIMPMGI:MGI:2674119MouseMGI:MGI:3699638|PMID:15132976
Biological ProcessGO:0019229regulation of vasoconstrictionCacna1cIMPMGI:MGI:2674119|MGI:MGI:2389040MouseMGI:MGI:3663939|PMID:14609949
Biological ProcessGO:0006939smooth muscle contractionCacna1cIMPMGI:MGI:2674119|MGI:MGI:2389040MouseMGI:MGI:3653822|PMID:16636102
Biological ProcessGO:0060083smooth muscle contraction involved in micturitionCacna1cIMPMGI:MGI:2674119MouseMGI:MGI:3699638|PMID:15132976
Biological ProcessGO:0007268synaptic transmissionCacna1cIMPMGI:MGI:2674114MouseMGI:MGI:3607037|PMID:16251435
Biological ProcessGO:0008542visual learningCacna1cIMPMGI:MGI:2674114MouseMGI:MGI:3607037|PMID:16251435

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory