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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
510

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:510

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:510
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0008083growth factor activityIGF2IDAHumanPMID:11500939
Molecular FunctionGO:0005158insulin receptor bindingIGF2IPIUniProtKB:P06213HumanPMID:12138094
Molecular FunctionGO:0005159insulin-like growth factor receptor bindingIgf2IPIUniProtKB:Q07113MouseMGI:MGI:2679358|PMID:14566968
Molecular FunctionGO:0005515protein bindingIGF2IPIUniProtKB:Q9PTH3HumanPMID:10611375
Molecular FunctionGO:0005515protein bindingIGF2IPIUniProtKB:P11717HumanPMID:18046459
Molecular FunctionGO:0005515protein bindingIgf2IPIUniProtKB:Q07079MouseMGI:MGI:2679358|PMID:14566968
Molecular FunctionGO:0005515protein bindingIgf2IPIUniProtKB:Q69ZQ1MouseMGI:MGI:4422154|PMID:19706595
Molecular FunctionGO:0005515protein bindingIgf2IPIUniProtKB:P12843RatRGD:729148|PMID:2538475
Molecular FunctionGO:0005515protein bindingIgf2IPIUniProtKB:P12843RatRGD:8553840|PMID:2974285
Molecular FunctionGO:0005515protein bindingIgf2IPIUniProtKB:P12843RatPMID:2538475
Molecular FunctionGO:0005515protein bindingIgf2IPIUniProtKB:P12843RatPMID:2974285
Molecular FunctionGO:0043539protein serine/threonine kinase activator activityIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Molecular FunctionGO:0030546receptor activator activityIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Cellular ComponentGO:0005615extracellular spaceIgf2IDAMouseMGI:MGI:3806392|PMID:18762576
Cellular ComponentGO:0005615extracellular spaceIgf2IDARatRGD:1624322|PMID:6390212
Cellular ComponentGO:0070062extracellular vesicular exosomeIGF2IDAHumanPMID:23376485
Biological ProcessGO:0031017exocrine pancreas developmentIgf2IMPMGI:MGI:2677156MouseMGI:MGI:2387729|PMID:12101187
Biological ProcessGO:0038028insulin receptor signaling pathway via phosphatidylinositol 3-kinaseIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:0007613memoryIgf2IMPRatRGD:5509946|PMID:21270887
Biological ProcessGO:0009887organ morphogenesisIgf2IMPMGI:MGI:2677156MouseMGI:MGI:2387729|PMID:12101187
Biological ProcessGO:0042104positive regulation of activated T cell proliferationIGF2IDAHumanPMID:15694994
Biological ProcessGO:0043085positive regulation of catalytic activityIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:2000467positive regulation of glycogen (starch) synthase activityIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:0045725positive regulation of glycogen biosynthetic processIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:0046628positive regulation of insulin receptor signaling pathwayIGF2IDAHumanPMID:11500939
Biological ProcessGO:0046628positive regulation of insulin receptor signaling pathwayIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:0043410positive regulation of MAPK cascadeIGF2IDAHumanPMID:11500939
Biological ProcessGO:0045840positive regulation of mitosisIGF2IDAHumanPMID:11500939
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:0051897positive regulation of protein kinase B signalingIGF2IDAHumanPMID:11500939
Biological ProcessGO:0001934positive regulation of protein phosphorylationIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:0071902positive regulation of protein serine/threonine kinase activityIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:2000273positive regulation of receptor activityIgf2IMPMouseMGI:MGI:4438697|PMID:20032056
Biological ProcessGO:0090031positive regulation of steroid hormone biosynthetic processIgf2IDARatRGD:1600072|PMID:17023532
Biological ProcessGO:0090031positive regulation of steroid hormone biosynthetic processIgf2IDARatPMID:17023532
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIgf2IGIMGI:MGI:87986MouseMGI:MGI:3806392|PMID:18762576
Biological ProcessGO:0042493response to drugIgf2IDARatRGD:5509951|PMID:18778817
Biological ProcessGO:0035094response to nicotineIgf2IDARatRGD:5509950|PMID:19494366
Biological ProcessGO:0014070response to organic cyclic compoundIgf2IDARatRGD:2311525|PMID:17407073
Biological ProcessGO:0051146striated muscle cell differentiationIgf2IGIMGI:MGI:96440MouseMGI:MGI:3806392|PMID:18762576

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory