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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
3856

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:3856

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:3856
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0071253connexin bindingGja5IPIRGD:2690RatRGD:7207849|PMID:11557558
Molecular FunctionGO:0005243gap junction channel activityGja5IDARatRGD:728713|PMID:1328644
Molecular FunctionGO:0086077gap junction channel activity involved in AV node cell-bundle of His cell electrical couplingGJA5IDAHumanPMID:22247482
Molecular FunctionGO:0086075gap junction channel activity involved in cardiac conduction electrical couplingGJA5IMPHumanPMID:16790700
Molecular FunctionGO:0086075gap junction channel activity involved in cardiac conduction electrical couplingGJA5IDAHumanPMID:23348765
Molecular FunctionGO:0055077gap junction hemi-channel activityGJA5IDAHumanPMID:23348765
Cellular ComponentGO:0042995cell projectionGja5IDARatRGD:7207813|PMID:16037574
Cellular ComponentGO:0005922connexon complexGJA5IDAHumanPMID:22247482
Cellular ComponentGO:0005922connexon complexGja5IDARatRGD:1598435|PMID:9851942
Cellular ComponentGO:0005922connexon complexGja5IDARatRGD:728713|PMID:1328644
Cellular ComponentGO:0005921gap junctionGJA5IDAHumanPMID:23348765
Cellular ComponentGO:0005921gap junctionGja5IDAMouseMGI:MGI:1197846|PMID:9501070
Cellular ComponentGO:0005887integral component of plasma membraneGJA5IDAHumanPMID:22247482
Cellular ComponentGO:0014704intercalated discGJA5IDAHumanPMID:16790700
Biological ProcessGO:0048844artery morphogenesisGja5IMPMouseMGI:MGI:4462093|PMID:20530546
Biological ProcessGO:0086014atrial cardiac muscle cell action potentialGJA5IMPHumanPMID:23348765
Biological ProcessGO:0003283atrial septum developmentGJA5IMPHumanPMID:22199024
Biological ProcessGO:0060413atrial septum morphogenesisGja5IMPMGI:MGI:2445238MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0003294atrial ventricular junction remodelingGja5IMPMGI:MGI:2445238MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0086067AV node cell to bundle of His cell communicationGja5IMPMGI:MGI:2445238MouseMGI:MGI:3696497|PMID:10515563
Biological ProcessGO:0086053AV node cell to bundle of His cell communication by electrical couplingGJA5IMPHumanPMID:22247482
Biological ProcessGO:0001568blood vessel developmentGja5IMPMGI:MGI:2445466MouseMGI:MGI:2445243|PMID:12435353
Biological ProcessGO:0086069bundle of His cell to Purkinje myocyte communicationGJA5IMPHumanPMID:22247482
Biological ProcessGO:0061337cardiac conductionGja5IMPMGI:MGI:2445238MouseMGI:MGI:1197846|PMID:9501070
Biological ProcessGO:0061337cardiac conductionGja5IMPMGI:MGI:2445466MouseMGI:MGI:1197847|PMID:9501069
Biological ProcessGO:0061337cardiac conductionGja5IMPMGI:MGI:2445238MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0061337cardiac conductionGja5IMPMGI:MGI:2445238MouseMGI:MGI:3696497|PMID:10515563
Biological ProcessGO:0061337cardiac conductionGja5IMPMGI:MGI:2445466MouseMGI:MGI:4412358|PMID:18599871
Biological ProcessGO:0003161cardiac conduction system developmentGja5IMPMGI:MGI:2445466MouseMGI:MGI:4412358|PMID:18599871
Biological ProcessGO:0003161cardiac conduction system developmentGja5IMPMouseMGI:MGI:5304955|PMID:22203979
Biological ProcessGO:0010643cell communication by chemical couplingGja5IDARatRGD:728713|PMID:1328644
Biological ProcessGO:0010644cell communication by electrical couplingGja5IDARatRGD:7207842|PMID:7554128
Biological ProcessGO:0086064cell communication by electrical coupling involved in cardiac conductionGJA5IDAHumanPMID:16790700
Biological ProcessGO:0086064cell communication by electrical coupling involved in cardiac conductionGJA5IDAHumanPMID:23348765
Biological ProcessGO:0086064cell communication by electrical coupling involved in cardiac conductionGja5IMPMGI:MGI:2445466MouseMGI:MGI:3664488|PMID:11046183
Biological ProcessGO:0086065cell communication involved in cardiac conductionGja5IMPMGI:MGI:2445238MouseMGI:MGI:2445988|PMID:10747000
Biological ProcessGO:0035050embryonic heart tube developmentGja5IMPMGI:MGI:2445466MouseMGI:MGI:2686766|PMID:14732399
Biological ProcessGO:0035050embryonic heart tube developmentGja5IMPMouseMGI:MGI:5304955|PMID:22203979
Biological ProcessGO:0030326embryonic limb morphogenesisGja5IMPMGI:MGI:2445466MouseMGI:MGI:3581374|PMID:15923624
Biological ProcessGO:0035922foramen ovale closureGja5IMPMGI:MGI:2445238MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0016264gap junction assemblyGJA5IMPHumanPMID:16790700
Biological ProcessGO:0016264gap junction assemblyGJA5IDAHumanPMID:22247482
Biological ProcessGO:0003174mitral valve developmentGJA5IMPHumanPMID:22199024
Biological ProcessGO:0045776negative regulation of blood pressureGja5IMPRatRGD:7207467|PMID:18046320
Biological ProcessGO:0003105negative regulation of glomerular filtrationGja5IMPRatRGD:7207472|PMID:17928514
Biological ProcessGO:0003151outflow tract morphogenesisGJA5IMPHumanPMID:22199024
Biological ProcessGO:0010652positive regulation of cell communication by chemical couplingGja5IMPRatRGD:7207816|PMID:15678088
Biological ProcessGO:0045907positive regulation of vasoconstrictionGja5IMPRatRGD:7207411|PMID:21414209
Biological ProcessGO:0045909positive regulation of vasodilationGja5IMPRatRGD:7207813|PMID:16037574
Biological ProcessGO:0006813potassium ion transportGja5IDARatRGD:7207842|PMID:7554128
Biological ProcessGO:0051259protein oligomerizationGja5IDARatRGD:7207849|PMID:11557558
Biological ProcessGO:0003193pulmonary valve formationGJA5IMPHumanPMID:22199024
Biological ProcessGO:0060371regulation of atrial cardiac muscle cell membrane depolarizationGJA5IMPHumanPMID:22247482
Biological ProcessGO:0060371regulation of atrial cardiac muscle cell membrane depolarizationGJA5IMPHumanPMID:23348765
Biological ProcessGO:0060371regulation of atrial cardiac muscle cell membrane depolarizationGja5IMPMGI:MGI:2445238MouseMGI:MGI:1197846|PMID:9501070
Biological ProcessGO:0060371regulation of atrial cardiac muscle cell membrane depolarizationGja5IMPMGI:MGI:2445238MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0060371regulation of atrial cardiac muscle cell membrane depolarizationGja5IMPMGI:MGI:2445238MouseMGI:MGI:3696497|PMID:10515563
Biological ProcessGO:0055117regulation of cardiac muscle contractionGJA5IMPHumanPMID:16790700
Biological ProcessGO:0055117regulation of cardiac muscle contractionGJA5IMPHumanPMID:22247482
Biological ProcessGO:0055117regulation of cardiac muscle contractionGJA5IMPHumanPMID:23348765
Biological ProcessGO:0086091regulation of heart rate by cardiac conductionGja5IMPMGI:MGI:2445466MouseMGI:MGI:3664488|PMID:11046183
Biological ProcessGO:1900825regulation of membrane depolarization during cardiac muscle cell action potentialGja5IMPMGI:MGI:2445238MouseMGI:MGI:1197846|PMID:9501070
Biological ProcessGO:1900133regulation of renin secretion into blood streamGja5IMPMGI:MGI:2445238MouseMGI:MGI:3783962|PMID:17255527
Biological ProcessGO:0003073regulation of systemic arterial blood pressureGja5IMPMGI:MGI:2445238MouseMGI:MGI:2445988|PMID:10747000
Biological ProcessGO:0042312regulation of vasodilationGja5IMPMGI:MGI:2445238MouseMGI:MGI:2445988|PMID:10747000
Biological ProcessGO:0060373regulation of ventricular cardiac muscle cell membrane depolarizationGja5IMPMGI:MGI:2445238MouseMGI:MGI:1197846|PMID:9501070
Biological ProcessGO:0060373regulation of ventricular cardiac muscle cell membrane depolarizationGja5IGIMGI:MGI:95713MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0060373regulation of ventricular cardiac muscle cell membrane depolarizationGja5IMPMGI:MGI:2445238MouseMGI:MGI:3696497|PMID:10515563
Biological ProcessGO:0060307regulation of ventricular cardiac muscle cell membrane repolarizationGja5IGIMGI:MGI:95713MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0060307regulation of ventricular cardiac muscle cell membrane repolarizationGja5IMPMGI:MGI:2445238MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0003071renal system process involved in regulation of systemic arterial blood pressureGja5IMPMGI:MGI:2445238MouseMGI:MGI:3783962|PMID:17255527
Biological ProcessGO:0086015SA node cell action potentialGja5IMPMGI:MGI:2445466MouseMGI:MGI:3664488|PMID:11046183
Biological ProcessGO:0003284septum primum developmentGja5IMPMGI:MGI:2445238MouseMGI:MGI:3639795|PMID:10969038
Biological ProcessGO:0001501skeletal system developmentGja5IMPMGI:MGI:2445466MouseMGI:MGI:3581374|PMID:15923624
Biological ProcessGO:0055085transmembrane transportGJA5IDAHumanPMID:23348765
Biological ProcessGO:0055085transmembrane transportGja5IDARatRGD:728713|PMID:1328644
Biological ProcessGO:0055085transmembrane transportGja5IDARatPMID:1328644
Biological ProcessGO:1990029vasomotionGja5IMPRatRGD:7207804|PMID:16815985
Biological ProcessGO:0086005ventricular cardiac muscle cell action potentialGja5IMPMGI:MGI:2445238MouseMGI:MGI:1197846|PMID:9501070
Biological ProcessGO:0003281ventricular septum developmentGJA5IMPHumanPMID:22199024
Biological ProcessGO:0060412ventricular septum morphogenesisGja5IMPMGI:MGI:2445238MouseMGI:MGI:3639795|PMID:10969038

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory