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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
3684

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:3684

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:3684
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003779actin bindingPFN1IPIUniProtKB:P68135HumanPMID:17914456
Molecular FunctionGO:0003779actin bindingPFN1IPIUniProtKB:P68135HumanPMID:7758455
Molecular FunctionGO:0000774adenyl-nucleotide exchange factor activityPFN1IDAHumanPMID:7758455
Molecular FunctionGO:0005546phosphatidylinositol-4,5-bisphosphate bindingPFN1IDAHumanPMID:7758455
Molecular FunctionGO:0005546phosphatidylinositol-4,5-bisphosphate bindingPfn1IDARatRGD:2324852|PMID:16741017
Molecular FunctionGO:0044822poly(A) RNA bindingPFN1IDAHumanPMID:22681889
Molecular FunctionGO:0070064proline-rich region bindingPFN1IPIUniProtKB:P50552HumanPMID:17914456
Molecular FunctionGO:0005515protein bindingPFN1IPIUniProtKB:P50552HumanPMID:23153535
Molecular FunctionGO:0005515protein bindingPFN1IPIUniProtKB:P70429HumanPMID:23153535
Molecular FunctionGO:0005515protein bindingPFN1IPIUniProtKB:O08816HumanPMID:9822597
Molecular FunctionGO:0005515protein bindingPFN1IPIUniProtKB:Q92558HumanPMID:9843499
Molecular FunctionGO:0005515protein bindingPfn1IPIUniProtKB:Q9ESJ5MouseMGI:MGI:2158592|PMID:11826110
Molecular FunctionGO:0005515protein bindingPfn1IPIUniProtKB:Q8R4U1MouseMGI:MGI:3526474|PMID:15615774
Molecular FunctionGO:0005515protein bindingPfn1IPIUniProtKB:P03372MouseMGI:MGI:5514125|PMID:23576398
Molecular FunctionGO:0005515protein bindingPfn1IPIRGD:69194RatRGD:2324853|PMID:12967995
Molecular FunctionGO:0005102receptor bindingPfn1IDARatRGD:2324858|PMID:10966486
Molecular FunctionGO:0017048Rho GTPase bindingPfn1IPIUniProtKB:P17081MouseMGI:MGI:3843447|PMID:10445846
Cellular ComponentGO:0072562blood microparticlePFN1IDAHumanPMID:22516433
Cellular ComponentGO:0005737cytoplasmPfn1IDAMouseMGI:MGI:2182205|PMID:11274401
Cellular ComponentGO:0005737cytoplasmPfn1IDARatRGD:2324853|PMID:12967995
Cellular ComponentGO:0070062extracellular vesicular exosomePFN1IDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular vesicular exosomePFN1IDAHumanPMID:20458337
Cellular ComponentGO:0070062extracellular vesicular exosomePFN1IDAHumanPMID:23376485
Cellular ComponentGO:0016020membranePFN1IDAHumanPMID:19946888
Cellular ComponentGO:0043005neuron projectionPfn1IDARatRGD:2324862|PMID:8106880
Cellular ComponentGO:0005634nucleusPfn1IDAMouseMGI:MGI:3526474|PMID:15615774
Cellular ComponentGO:0045202synapsePfn1IDARatRGD:2324853|PMID:12967995
Biological ProcessGO:0032232negative regulation of actin filament bundle assemblyPFN1IMPHumanPMID:23153535
Biological ProcessGO:0030837negative regulation of actin filament polymerizationPFN1IDAHumanPMID:7758455
Biological ProcessGO:0051497negative regulation of stress fiber assemblyPFN1IMPHumanPMID:23153535
Biological ProcessGO:0001843neural tube closurePfn1IGIMGI:MGI:108360MouseMGI:MGI:1331576|PMID:10069337
Biological ProcessGO:0030838positive regulation of actin filament polymerizationPFN1IGIUniProtKB:P35080HumanPMID:23153535
Biological ProcessGO:0032781positive regulation of ATPase activityPFN1IDAHumanPMID:7758455
Biological ProcessGO:0051054positive regulation of DNA metabolic processPfn1IDARatRGD:2324858|PMID:10966486
Biological ProcessGO:0010634positive regulation of epithelial cell migrationPFN1IMPHumanPMID:23153535
Biological ProcessGO:1900029positive regulation of ruffle assemblyPFN1IMPHumanPMID:23153535
Biological ProcessGO:0051496positive regulation of stress fiber assemblyPfn1IMPRatRGD:2324854|PMID:12740026
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPfn1IDARatRGD:2324858|PMID:10966486
Biological ProcessGO:0050434positive regulation of viral transcriptionPfn1IMPRatRGD:2324854|PMID:12740026
Biological ProcessGO:0006357regulation of transcription from RNA polymerase II promoterPfn1IGIMGI:MGI:2446472MouseMGI:MGI:3526474|PMID:15615774

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory