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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
22758

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:22758

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:22758
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0051015actin filament bindingADD1IDAHumanPMID:7642559
Molecular FunctionGO:0045296cadherin bindingADD1IDAHumanPMID:25468996
Molecular FunctionGO:0005515protein bindingAdd1IPIRGD:2043RatRGD:631726|PMID:7592723
Molecular FunctionGO:0046982protein heterodimerization activityADD1IPIUniProtKB:P35612HumanPMID:7642559
Molecular FunctionGO:0042803protein homodimerization activityADD1IPIUniProtKB:P35611HumanPMID:7642559
Molecular FunctionGO:0003723RNA bindingADD1IDAHumanPMID:22658674
Molecular FunctionGO:0030507spectrin bindingADD1IDAHumanPMID:7642559
Molecular FunctionGO:0005198structural molecule activityAdd1IDAMouseMGI:MGI:2149009|PMID:10485892
Molecular FunctionGO:0042608T cell receptor bindingAdd1IDARatRGD:1624956|PMID:15163540
Molecular FunctionGO:0008134transcription factor bindingADD1IPIUniProtKB:P22670HumanPMID:16289097
Cellular ComponentGO:0005913cell-cell adherens junctionADD1IDAHumanPMID:25978380
Cellular ComponentGO:0005913cell-cell adherens junctionAdd1IMPMouseMGI:MGI:5796260|PMID:25978380
Cellular ComponentGO:0005737cytoplasmADD1IDAHumanPMID:25978380
Cellular ComponentGO:0005856cytoskeletonAdd1IDAMouseMGI:MGI:2149009|PMID:10485892
Cellular ComponentGO:0030425dendriteAdd1IDARatRGD:1624954|PMID:8624703
Cellular ComponentGO:0043197dendritic spineAdd1IDARatRGD:1624954|PMID:8624703
Cellular ComponentGO:0008290F-actin capping protein complexADD1IDAHumanPMID:8626479
Cellular ComponentGO:0005925focal adhesionADD1IDAHumanPMID:21423176
Cellular ComponentGO:0016020membraneAdd1IDAMouseMGI:MGI:2149009|PMID:10485892
Cellular ComponentGO:0016604nuclear bodyADD1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005654nucleoplasmADD1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusADD1IDAHumanPMID:16289097
Cellular ComponentGO:0048471perinuclear region of cytoplasmAdd1IDARatRGD:5148002|PMID:20493242
Cellular ComponentGO:0005886plasma membraneADD1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005886plasma membraneADD1IDAHumanPMID:25978380
Cellular ComponentGO:0005886plasma membraneAdd1IMPMouseMGI:MGI:5796260|PMID:25978380
Cellular ComponentGO:0014069postsynaptic densityAdd1IDARatRGD:5147998|PMID:11226670
Cellular ComponentGO:0045202synapseAdd1IDARatRGD:1624954|PMID:8624703
Biological ProcessGO:0051017actin filament bundle assemblyADD1IDAHumanPMID:3693401
Biological ProcessGO:0051016barbed-end actin filament cappingADD1IDAHumanPMID:8626479
Biological ProcessGO:0000902cell morphogenesisAdd1IMPMGI:MGI:3799499MouseMGI:MGI:3806792|PMID:18723693
Biological ProcessGO:0006884cell volume homeostasisAdd1IMPMGI:MGI:3799499MouseMGI:MGI:3806792|PMID:18723693
Biological ProcessGO:0071277cellular response to calcium ionADD1IDAHumanPMID:25978380
Biological ProcessGO:0071277cellular response to calcium ionAdd1IDAMouseMGI:MGI:5796260|PMID:25978380
Biological ProcessGO:0071300cellular response to retinoic acidAdd1IDARatRGD:5148002|PMID:20493242
Biological ProcessGO:0030218erythrocyte differentiationAdd1IMPMGI:MGI:3799499MouseMGI:MGI:3806792|PMID:18723693
Biological ProcessGO:0020027hemoglobin metabolic processAdd1IMPMGI:MGI:3799499MouseMGI:MGI:3806792|PMID:18723693
Biological ProcessGO:0048873homeostasis of number of cells within a tissueAdd1IMPMGI:MGI:3799499MouseMGI:MGI:3806792|PMID:18723693
Biological ProcessGO:0001701in utero embryonic developmentAdd1IMPMGI:MGI:3799499MouseMGI:MGI:3806792|PMID:18723693
Biological ProcessGO:0035264multicellular organism growthAdd1IMPMGI:MGI:3799499MouseMGI:MGI:3806792|PMID:18723693
Biological ProcessGO:0030837negative regulation of actin filament polymerizationAdd1IMPRatRGD:7174724|PMID:8675693
Biological ProcessGO:1903393positive regulation of adherens junction organizationADD1IDAHumanPMID:25978380
Biological ProcessGO:1903393positive regulation of adherens junction organizationAdd1IMPMouseMGI:MGI:5796260|PMID:25978380
Biological ProcessGO:0045766positive regulation of angiogenesisAdd1IDARatRGD:5148005|PMID:17512505
Biological ProcessGO:0045807positive regulation of endocytosisAdd1IMPRatRGD:5148004|PMID:18524856
Biological ProcessGO:1903142positive regulation of establishment of endothelial barrierADD1IDAHumanPMID:25978380
Biological ProcessGO:1903142positive regulation of establishment of endothelial barrierAdd1IMPMouseMGI:MGI:5796260|PMID:25978380
Biological ProcessGO:0032092positive regulation of protein bindingADD1IDAHumanPMID:3693401
Biological ProcessGO:0032092positive regulation of protein bindingADD1IDAHumanPMID:7642559

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/31/2018
MGI 6.12
The Jackson Laboratory