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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
21053

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:21053

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:21053
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005515protein bindingSIAH2IPIUniProtKB:Q7Z6J0HumanPMID:21586138
Molecular FunctionGO:0005515protein bindingSIAH2IPIUniProtKB:Q92995HumanPMID:21659512
Molecular FunctionGO:0005515protein bindingSIAH2IPIUniProtKB:P35372HumanPMID:23840749
Molecular FunctionGO:0005515protein bindingSiah2IPIUniProtKB:O08715MouseMGI:MGI:5508596|PMID:18323779
Molecular FunctionGO:0005515protein bindingSiah2IPIUniProtKB:P10275MouseMGI:MGI:5490696|PMID:23518348
Molecular FunctionGO:0005515protein bindingSiah2IPIRGD:3802RatRGD:633984|PMID:11786535
Molecular FunctionGO:0031624ubiquitin conjugating enzyme bindingSiah2IDARatRGD:633984|PMID:11786535
Molecular FunctionGO:0004842ubiquitin-protein transferase activitySIAH2EXPHumanPMID:19028597
Cellular ComponentGO:0005829cytosolSIAH2IDAHumanPMID:21586138
Cellular ComponentGO:0005829cytosolSiah2IDARatRGD:633984|PMID:11786535
Cellular ComponentGO:0005769early endosomeSiah2IDARatRGD:633984|PMID:11786535
Cellular ComponentGO:0043231intracellular membrane-bounded organelleSIAH2IDAHumanGO_REF:0000052
Cellular ComponentGO:0043005neuron projectionSiah2IDARatRGD:633984|PMID:11786535
Cellular ComponentGO:0043025neuronal cell bodySiah2IDARatRGD:633984|PMID:11786535
Cellular ComponentGO:0005654nucleoplasmSIAH2IDAHumanGO_REF:0000052
Biological ProcessGO:0044257cellular protein catabolic processSIAH2IGIUniProtKB:P25054HumanPMID:12952940
Biological ProcessGO:0044257cellular protein catabolic processSIAH2IGIUniProtKB:P41221HumanPMID:12952940
Biological ProcessGO:0043066negative regulation of apoptotic processSIAH2IMPHumanPMID:21586138
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwaySIAH2IGIUniProtKB:P25054HumanPMID:12952940
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwaySIAH2IGIUniProtKB:P41221HumanPMID:12952940
Biological ProcessGO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic processSIAH2IMPHumanPMID:21586138
Biological ProcessGO:2001237negative regulation of extrinsic apoptotic signaling pathwaySIAH2IMPHumanPMID:21586138
Biological ProcessGO:0031396regulation of protein ubiquitinationSiah2IDARatRGD:633984|PMID:11786535

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory