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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
20750

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:20750

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:20750
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005109frizzled bindingFZD1IPIUniProtKB:Q99972HumanPMID:19188438
Molecular FunctionGO:0042802identical protein bindingFzd1IPIUniProtKB:Q08463RatRGD:8553956|PMID:14688793
Molecular FunctionGO:0042802identical protein bindingFzd1IPIUniProtKB:Q08463RatPMID:14688793
Molecular FunctionGO:0030165PDZ domain bindingFZD1IPIUniProtKB:O14640HumanPMID:19388021
Molecular FunctionGO:0030165PDZ domain bindingFZD1IPIUniProtKB:O14641HumanPMID:19388021
Molecular FunctionGO:0030165PDZ domain bindingFZD1IPIUniProtKB:Q92997HumanPMID:19388021
Molecular FunctionGO:0005515protein bindingFZD1IPIUniProtKB:Q8N474HumanPMID:19277043
Molecular FunctionGO:0005515protein bindingFzd1IPIUniProtKB:Q08464RatRGD:8553956|PMID:14688793
Molecular FunctionGO:0005515protein bindingFzd1IPIUniProtKB:Q08464RatPMID:14688793
Molecular FunctionGO:0046982protein heterodimerization activityFzd1IPIUniProtKB:Q08464RatRGD:8553956|PMID:14688793
Molecular FunctionGO:0046982protein heterodimerization activityFzd1IPIUniProtKB:Q08464RatPMID:14688793
Molecular FunctionGO:0042803protein homodimerization activityFzd1IPIUniProtKB:Q08463RatRGD:8553956|PMID:14688793
Molecular FunctionGO:0042803protein homodimerization activityFzd1IPIUniProtKB:Q08463RatPMID:14688793
Molecular FunctionGO:0005102receptor bindingFZD1IPIUniProtKB:O75581HumanPMID:14739301
Molecular FunctionGO:0042813Wnt-activated receptor activityFZD1IDAHumanPMID:10557084
Molecular FunctionGO:0017147Wnt-protein bindingFZD1IPIUniProtKB:P09544HumanPMID:10557084
Molecular FunctionGO:0017147Wnt-protein bindingFZD1IPIUniProtKB:P22725HumanPMID:10557084
Molecular FunctionGO:0017147Wnt-protein bindingFZD1IPIUniProtKB:P56703HumanPMID:10557084
Molecular FunctionGO:0017147Wnt-protein bindingFzd1IPIUniProtKB:P28047MouseMGI:MGI:3581375|PMID:15923619
Cellular ComponentGO:0009986cell surfaceFZD1IDAHumanPMID:19643732
Cellular ComponentGO:0043005neuron projectionFzd1IDARatRGD:4107041|PMID:19883499
Cellular ComponentGO:0005886plasma membraneFzd1IDARatRGD:8553956|PMID:14688793
Cellular ComponentGO:0005886plasma membraneFzd1IDARatPMID:14688793
Biological ProcessGO:0035425autocrine signalingFZD1IDAHumanPMID:10557084
Biological ProcessGO:0060070canonical Wnt signaling pathwayFZD1IDAHumanPMID:10557084
Biological ProcessGO:0060070canonical Wnt signaling pathwayFZD1IDAHumanPMID:14739301
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd1IMPMouseMGI:MGI:3045675|PMID:15143170
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd1IDARatRGD:8553956|PMID:14688793
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd1IDARatRGD:8554426|PMID:18945944
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd1IDARatPMID:14688793
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd1IDARatPMID:18945944
Biological ProcessGO:0044338canonical Wnt signaling pathway involved in mesenchymal stem cell differentiationFZD1IMPHumanPMID:20039315
Biological ProcessGO:0044339canonical Wnt signaling pathway involved in osteoblast differentiationFZD1IMPHumanPMID:20039315
Biological ProcessGO:0007267cell-cell signalingFZD1IDAHumanPMID:10557084
Biological ProcessGO:0007267cell-cell signalingFzd1IDAMouseMGI:MGI:3577819|PMID:15809042
Biological ProcessGO:0030855epithelial cell differentiationFzd1IDAMouseMGI:MGI:3577819|PMID:15809042
Biological ProcessGO:0030855epithelial cell differentiationFzd1IGIMGI:MGI:103124MouseMGI:MGI:3577819|PMID:15809042
Biological ProcessGO:0060022hard palate developmentFzd1IGIMGI:MGI:1888513MouseMGI:MGI:4837757|PMID:20940229
Biological ProcessGO:0003149membranous septum morphogenesisFzd1IGIMGI:MGI:1888513|MGI:MGI:2135272MouseMGI:MGI:4837757|PMID:20940229
Biological ProcessGO:0003150muscular septum morphogenesisFzd1IGIMGI:MGI:1888513|MGI:MGI:2135272MouseMGI:MGI:4837757|PMID:20940229
Biological ProcessGO:0030514negative regulation of BMP signaling pathwayFzd1IDAMouseMGI:MGI:3033512|PMID:14627707
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayFzd1IDAMouseMGI:MGI:3033546|PMID:14662765
Biological ProcessGO:0035414negative regulation of catenin import into nucleusFzd1IDAMouseMGI:MGI:3033512|PMID:14627707
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedFzd1IMPMouseMGI:MGI:3656361|PMID:16936075
Biological ProcessGO:0003151outflow tract morphogenesisFzd1IGIMGI:MGI:1888513MouseMGI:MGI:4837757|PMID:20940229
Biological ProcessGO:0090179planar cell polarity pathway involved in neural tube closureFzd1IGIMGI:MGI:1888513|MGI:MGI:2135272MouseMGI:MGI:4837757|PMID:20940229
Biological ProcessGO:0001934positive regulation of protein phosphorylationFzd1IMPMouseMGI:MGI:3045675|PMID:15143170
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityFZD1IDAHumanPMID:10557084
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityFZD1IDAHumanPMID:14739301
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityFzd1IDARatRGD:8553956|PMID:14688793
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityFzd1IDARatRGD:8554426|PMID:18945944
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityFzd1IDARatPMID:14688793
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityFzd1IDARatPMID:18945944
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedFZD1IDAHumanPMID:18929644
Biological ProcessGO:0042493response to drugFZD1IMPHumanPMID:19421142
Biological ProcessGO:0060412ventricular septum morphogenesisFzd1IGIMGI:MGI:1888513MouseMGI:MGI:4837757|PMID:20940229
Biological ProcessGO:0016055Wnt signaling pathwayFzd1IGIMGI:MGI:98961|MGI:MGI:1278315|MGI:MGI:2136761MouseMGI:MGI:3581375|PMID:15923619
Biological ProcessGO:0016055Wnt signaling pathwayFzd1IDARatRGD:4107043|PMID:10559239

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory