Comparative GO Graph (mouse, human, rat)

• Source: HomoloGene (Release 68, May 6, 2014)
• Class ID: 20700

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

• This class contains
  • Human genes TSPAN6
  • Mouse genes Tspan6
  • Rat genes Tspan6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD.
• Only experimental annotations are displayed: EXP, IDA, IGI, IMP, IPI. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:20700

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TSPAN6	IPI	UniProtKB:Q7Z434	Human	PMID:22908223
Molecular Function	GO:0005515	protein binding	TSPAN6	IPI	UniProtKB:Q86WV6	Human	PMID:22908223
Molecular Function	GO:0005515	protein binding	TSPAN6	IPI	UniProtKB:Q9BYX4	Human	PMID:22908223
Molecular Function	GO:0005515	protein binding	TSPAN6	IPI	UniProtKB:Q9UL19	Human	PMID:22908223
Molecular Function	GO:0004871	signal transducer activity	TSPAN6	IMP		Human	PMID:12761501
Cellular Component	GO:0070062	extracellular exosome	TSPAN6	IDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TSPAN6	IDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	TSPAN6	IDA		Human	PMID:23533145
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	TSPAN6	IDA		Human	PMID:22908223
Biological Process	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	TSPAN6	IMP		Human	PMID:22908223
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TSPAN6	IMP		Human	PMID:12761501

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction