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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
18868

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:18868

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:18868
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0035438cyclic-di-GMP bindingTMEM173IDAHumanPMID:22705373
Molecular FunctionGO:0035438cyclic-di-GMP bindingTmem173IDAMouseMGI:MGI:5487515|PMID:21947006
Molecular FunctionGO:0035438cyclic-di-GMP bindingTmem173IDAMouseMGI:MGI:5700266|PMID:26300263
Molecular FunctionGO:0061507cyclic-GMP-AMP bindingTMEM173IDAHumanPMID:26669264
Molecular FunctionGO:0061507cyclic-GMP-AMP bindingTmem173IDAMouseMGI:MGI:5700266|PMID:26300263
Molecular FunctionGO:0061507cyclic-GMP-AMP bindingTmem173IDAMouseMGI:MGI:5487473|PMID:23258412
Molecular FunctionGO:0061507cyclic-GMP-AMP bindingTmem173IDAMouseMGI:MGI:5787716|PMID:26669264
Molecular FunctionGO:0061507cyclic-GMP-AMP bindingTmem173IDARatRGD:11344949|PMID:26669264
Molecular FunctionGO:0042802identical protein bindingTMEM173IPIUniProtKB:Q86WV6HumanPMID:23542348
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:O95786HumanPMID:18724357
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q7Z434HumanPMID:18818105
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:P09913HumanPMID:19416887
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:P09914HumanPMID:19416887
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q9UHD2HumanPMID:19416887
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q16666HumanPMID:20890285
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:O15260HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:O94822HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:O95470HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:P39656HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:P46977HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:P51617HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q96A33HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q96N66HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q9UHD2HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:P42226HumanPMID:22000020
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q7Z434HumanPMID:22000020
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:O43657HumanPMID:22908223
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q7Z434HumanPMID:22908223
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:P27958:PRO_0000037575HumanPMID:22911572
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q7Z434HumanPMID:22911572
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q7Z434HumanPMID:23542348
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q99IB8:PRO_0000045601HumanPMID:23542348
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q9UHD2HumanPMID:23542348
Molecular FunctionGO:0005515protein bindingTMEM173IPIUniProtKB:Q7RTR2HumanPMID:24560620
Molecular FunctionGO:0005515protein bindingTmem173IPIUniProtKB:Q91VN6|UniProtKB:Q9WUN2MouseMGI:MGI:5508701|PMID:23142775
Molecular FunctionGO:0005515protein bindingTmem173IPIUniProtKB:Q9WUN2MouseMGI:MGI:5295319|PMID:22000020
Molecular FunctionGO:0005515protein bindingTmem173IPIUniProtKB:Q91VN6MouseMGI:MGI:5291856|PMID:21892174
Molecular FunctionGO:0005515protein bindingTmem173IPIUniProtKB:Q9WUN2MouseMGI:MGI:5568884|PMID:24560620
Molecular FunctionGO:0042803protein homodimerization activityTMEM173IDAHumanPMID:19433799
Molecular FunctionGO:0042803protein homodimerization activityTMEM173IDAHumanPMID:21074459
Molecular FunctionGO:0042803protein homodimerization activityTMEM173IDAHumanPMID:22705373
Molecular FunctionGO:0019901protein kinase bindingTMEM173IDAHumanPMID:18818105
Molecular FunctionGO:0019901protein kinase bindingTMEM173IPIUniProtKB:Q9WUN2HumanPMID:21074459
Molecular FunctionGO:0008134transcription factor bindingTMEM173IDAHumanPMID:18818105
Molecular FunctionGO:0031625ubiquitin protein ligase bindingTmem173IPIUniProtKB:Q80VI1MouseMGI:MGI:4849871|PMID:21074459
Cellular ComponentGO:0005737cytoplasmTmem173IDAMouseMGI:MGI:5568884|PMID:24560620
Cellular ComponentGO:0005829cytosolTMEM173IDAHumanGO_REF:0000052
Cellular ComponentGO:0005783endoplasmic reticulumTmem173IDAMouseMGI:MGI:5291856|PMID:21892174
Cellular ComponentGO:0005783endoplasmic reticulumTmem173IDAMouseMGI:MGI:4414713|PMID:19926846
Cellular ComponentGO:0005789endoplasmic reticulum membraneTMEM173IDAHumanPMID:19433799
Cellular ComponentGO:0005789endoplasmic reticulum membraneTmem173IDAMouseMGI:MGI:4365649|PMID:19776740
Cellular ComponentGO:0005794Golgi apparatusTmem173IDAMouseMGI:MGI:4414713|PMID:19926846
Cellular ComponentGO:0005741mitochondrial outer membraneTMEM173IDAHumanPMID:18818105
Cellular ComponentGO:0005654nucleoplasmTMEM173IDAHumanGO_REF:0000052
Cellular ComponentGO:0048471perinuclear region of cytoplasmTmem173IDAMouseMGI:MGI:4365649|PMID:19776740
Cellular ComponentGO:0005777peroxisomeTmem173IDAMouseMGI:MGI:5432265|PMID:22745163
Biological ProcessGO:0002218activation of innate immune responseTMEM173IMPHumanPMID:18818105
Biological ProcessGO:0002218activation of innate immune responseTmem173IMPMouseMGI:MGI:5487473|PMID:23258412
Biological ProcessGO:0002218activation of innate immune responseTmem173IMPMouseMGI:MGI:5487515|PMID:21947006
Biological ProcessGO:0071360cellular response to exogenous dsRNATMEM173IMPHumanPMID:18818105
Biological ProcessGO:0035458cellular response to interferon-betaTmem173IMPMouseMGI:MGI:5291856|PMID:21892174
Biological ProcessGO:0071407cellular response to organic cyclic compoundTMEM173IDAHumanPMID:26669264
Biological ProcessGO:0071407cellular response to organic cyclic compoundTmem173IDAMouseMGI:MGI:5787716|PMID:26669264
Biological ProcessGO:0071407cellular response to organic cyclic compoundTmem173IDARatRGD:11344949|PMID:26669264
Biological ProcessGO:0051607defense response to virusTMEM173IDAHumanPMID:21074459
Biological ProcessGO:0051607defense response to virusTmem173IMPMouseMGI:MGI:4365649|PMID:19776740
Biological ProcessGO:0051607defense response to virusTmem173IMPMouseMGI:MGI:5291856|PMID:21892174
Biological ProcessGO:0045087innate immune responseTMEM173IMPHumanPMID:19433799
Biological ProcessGO:0045087innate immune responseTMEM173IDAHumanPMID:21074459
Biological ProcessGO:0045087innate immune responseTmem173IMPMouseMGI:MGI:4365649|PMID:19776740
Biological ProcessGO:0045087innate immune responseTmem173IMPMouseMGI:MGI:3849536|PMID:19433799
Biological ProcessGO:0032608interferon-beta productionTMEM173IMPHumanPMID:19433799
Biological ProcessGO:0032608interferon-beta productionTMEM173IDAHumanPMID:21074459
Biological ProcessGO:0032608interferon-beta productionTmem173IMPMouseMGI:MGI:4365649|PMID:19776740
Biological ProcessGO:0032608interferon-beta productionTmem173IMPMouseMGI:MGI:3849536|PMID:19433799
Biological ProcessGO:0002230positive regulation of defense response to virus by hostTMEM173IMPHumanPMID:18818105
Biological ProcessGO:0032092positive regulation of protein bindingTMEM173IDAHumanPMID:18818105
Biological ProcessGO:0033160positive regulation of protein import into nucleus, translocationTMEM173IDAHumanPMID:18818105
Biological ProcessGO:0042993positive regulation of transcription factor import into nucleusTMEM173IDAHumanPMID:18818105
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTMEM173IDAHumanPMID:18818105
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTmem173IDAMouseMGI:MGI:5291856|PMID:21892174
Biological ProcessGO:0032481positive regulation of type I interferon productionTMEM173IDAHumanPMID:26669264
Biological ProcessGO:0032481positive regulation of type I interferon productionTmem173IDAMouseMGI:MGI:5787716|PMID:26669264
Biological ProcessGO:0032481positive regulation of type I interferon productionTmem173IDARatRGD:11344949|PMID:26669264

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory