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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1207

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:1207

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:1207
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:P58753HumanPMID:11544529
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:P68467HumanPMID:18636090
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:P10398HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:P46977HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:P58753HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:Q13148HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:Q5D1E8HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:Q6PDS3HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingIRAK2IPIUniProtKB:Q9H0E2HumanPMID:21903422
Molecular FunctionGO:0005515protein bindingIrak2IPIUniProtKB:P22366MouseMGI:MGI:2149909|PMID:11544529
Molecular FunctionGO:0046982protein heterodimerization activityIRAK2IPIUniProtKB:P51617HumanPMID:10383454
Molecular FunctionGO:0046982protein heterodimerization activityIRAK2IPIUniProtKB:Q9Y616HumanPMID:10383454
Molecular FunctionGO:0042803protein homodimerization activityIRAK2IPIUniProtKB:O43187HumanPMID:10383454
Biological ProcessGO:0070498interleukin-1-mediated signaling pathwayIRAK2IMPHumanPMID:10383454
Biological ProcessGO:0031663lipopolysaccharide-mediated signaling pathwayIrak2IDAMouseMGI:MGI:3046371|PMID:15082713
Biological ProcessGO:0032088negative regulation of NF-kappaB transcription factor activityIRAK2IMPHumanPMID:10383454
Biological ProcessGO:0043433negative regulation of sequence-specific DNA binding transcription factor activityIrak2IDAMouseMGI:MGI:3046371|PMID:15082713
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityIRAK2IMPHumanPMID:10383454
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityIrak2IDAMouseMGI:MGI:3046371|PMID:15082713
Biological ProcessGO:0001959regulation of cytokine-mediated signaling pathwayIRAK2IMPHumanPMID:10383454
Biological ProcessGO:0070555response to interleukin-1IRAK2IMPHumanPMID:10383454

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory