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Comparative GO Graph (mouse, human, rat)
Class ID
HomoloGene (Release 68, May 6, 2014)

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:11032

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:11032
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005126cytokine receptor bindingIl21IDAMouseMGI:MGI:1926991|PMID:11081504
Molecular FunctionGO:0005134interleukin-2 receptor bindingIL21IPIUniProtKB:P31785HumanPMID:12504082
Biological ProcessGO:0048469cell maturationIL21IDAHumanPMID:14635054
Biological ProcessGO:0030890positive regulation of B cell proliferationIL21IDAHumanPMID:17673207
Biological ProcessGO:0008284positive regulation of cell proliferationIL21IDAHumanPMID:17673207
Biological ProcessGO:0001819positive regulation of cytokine productionIL21IDAHumanPMID:19322899
Biological ProcessGO:0045078positive regulation of interferon-gamma biosynthetic processIl21IDAMouseMGI:MGI:3028812|PMID:14764669
Biological ProcessGO:0032733positive regulation of interleukin-10 productionIl21IDAMouseMGI:MGI:3028812|PMID:14764669
Biological ProcessGO:0032740positive regulation of interleukin-17 productionIL21IDAHumanPMID:16482511
Biological ProcessGO:0002729positive regulation of natural killer cell cytokine productionIl21IDAMouseMGI:MGI:3028812|PMID:14764669
Biological ProcessGO:0032825positive regulation of natural killer cell differentiationIl21IDAMouseMGI:MGI:3028812|PMID:14764669
Biological ProcessGO:0045954positive regulation of natural killer cell mediated cytotoxicityIL21IDAHumanPMID:18005035
Biological ProcessGO:0045954positive regulation of natural killer cell mediated cytotoxicityIl21IDAMouseMGI:MGI:3028812|PMID:14764669
Biological ProcessGO:0042102positive regulation of T cell proliferationIL21IDAHumanPMID:15207081
Biological ProcessGO:0042102positive regulation of T cell proliferationIL21IDAHumanPMID:17673207

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory