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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MKS1 HGNC:7121 (HGNC)
54903 (Entrez Gene)
609883 (OMIM)
MKS1 (MyGene.info)
HGNC homology
Chr17 q22 Chr17:58205436-58219605 (-)
Bardet-Biedl syndrome 13
Joubert syndrome 28
Meckel syndrome 1
Q9NXB0 (UniProt | EBI)
NM_001165927 (RefSeq)
mouse Mks1 MGI:3584243 (MGI)
380718 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 52.24 cM Chr11:87853215-87863803 (+)
atrioventricular septal defect
Meckel syndrome
tetralogy of Fallot
ENSMUSG00000034121 (Ensembl Gene Model)
ENSMUSP00000043790 (Ensembl)
ENSMUST00000038196 (Ensembl)
rat Mks1 287612 (Entrez Gene)
Chr10 q26 Q499Q5 (UniProt | EBI)
NM_001034917 (RefSeq)
chimpanzee MKS1 455153 (Entrez Gene)
Chr17 XP_024206301 (RefSeq)
cattle MKS1 101905689 (Entrez Gene)
Chr19 NP_001026936 (RefSeq)
NM_001031766 (RefSeq)
dog MKS1 100855916 (Entrez Gene)
Chr9 XP_003639341 (RefSeq)
chicken MKS1 417457 (Entrez Gene)
Chr19 XP_415705 (RefSeq)
zebrafish mks1 556706 (Entrez Gene)
Chr5 NP_001070841 (RefSeq)
NM_001077373 (RefSeq)
frog, western clawed mks1 733975 (Entrez Gene)
Chr2 NP_001039150 (RefSeq)
NM_001045685 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory