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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPG21 HGNC:20373 (HGNC)
51324 (Entrez Gene)
608181 (OMIM)
HGNC homology
Chr15 q22.31 Chr15:64963021-64989946 (-)
Mast Syndrome
Q9NZD8 (UniProt | EBI)
NM_016630 (RefSeq)
mouse Spg21 MGI:106403 (MGI)
27965 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 35.32 cM Chr9:65460937-65488470 (+)
27965 (NCBI Gene Model)
Q9CQC8 (UniProt | EBI)
NM_138584 (RefSeq)
rat Spg21 300791 (Entrez Gene)
Chr8 q24 Q5XIC4 (UniProt | EBI)
NM_001006987 (RefSeq)
chimpanzee SPG21 453510 (Entrez Gene)
Chr15 XP_003314760 (RefSeq)
rhesus macaque SPG21 712815 (Entrez Gene)
Chr7 NP_001181819 (RefSeq)
NM_001194890 (RefSeq)
cattle SPG21 404069 (Entrez Gene)
Chr10 Q8MJJ1 (UniProt | EBI)
NM_205772 (RefSeq)
dog SPG21 487599 (Entrez Gene)
Chr30 XP_005638576 (RefSeq)
chicken SPG21 415526 (Entrez Gene)
Chr10 NP_001185533 (RefSeq)
NM_001198604 (RefSeq)
western clawed frog spg21 549880 (Entrez Gene)
ChrUN NP_001017126 (RefSeq)
NM_001017126 (RefSeq)
zebrafish spg21 406704 (Entrez Gene)
Chr7 Q6PC62 (UniProt | EBI)
NM_213395 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory