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Vertebrate Homology Class
Class ID
HomoloGene (Release 67, Dec 12, 2012)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CASP4 HGNC:1505 (HGNC)
837 (Entrez Gene)
602664 (OMIM)
Chr11 q22.2-q22.3 Chr11:104942867-104968598 (-)
P49662 (UniProt | EBI)
NM_001225 (RefSeq)
mouse Casp4 MGI:107700 (MGI)
12363 (Entrez Gene)
Gene Tree
Chr9 2.46 cM Chr9:5308828-5336783 (+)
OTTMUSG00000033830 (VEGA)
OTTMUSP00000046015 (VEGA)
OTTMUST00000085221 (VEGA)
rat Casp4 114555 (Entrez Gene)
Chr8 q11 NP_446188 (RefSeq)
NM_053736 (RefSeq)
chimpanzee CASP4 451518 (Entrez Gene)
Chr11 XP_508729 (RefSeq)
rhesus macaque CASP4 704864 (Entrez Gene)
Chr14 NP_001247885 (RefSeq)
NM_001260956 (RefSeq)
cattle CASP4 338039 (Entrez Gene)
Chr15 O75601 (UniProt | EBI)
NM_176638 (RefSeq)
dog CASP4 403724 (Entrez Gene)
Chr5 Q9MZV7 (UniProt | EBI)
NM_001003125 (RefSeq)
zebrafish caspa 57933 (Entrez Gene)
Chr16 NP_571580 (RefSeq)
NM_131505 (RefSeq)
caspb 259303 (Entrez Gene)
Chr1 NP_690840 (RefSeq)
NM_152884 (RefSeq)
caspbl 566185 (Entrez Gene)
Chr1 NP_001139064 (RefSeq)
NM_001145592 (RefSeq)
si:ch211-233g6.8 100333888 (Entrez Gene)
Chr1 XP_003197824 (RefSeq)
zgc:171731 563034 (Entrez Gene)
Chr7 NP_001103182 (RefSeq)
NM_001109712 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.17
The Jackson Laboratory