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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ISOC1 HGNC:24254 (HGNC)
51015 (Entrez Gene)
HGNC homology
Chr5 q23.3 Chr5:129094749-129114028 (+)
Q96CN7 (UniProt | EBI)
NM_016048 (RefSeq)
mouse Isoc1 MGI:1913557 (MGI)
66307 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 33.71 cM Chr18:58659482-58679570 (+)
66307 (NCBI Gene Model)
Q91V64 (UniProt | EBI)
NM_025478 (RefSeq)
rat Isoc1 364879 (Entrez Gene)
Chr18 q12.1 Q6I7R3 (UniProt | EBI)
NM_001014242 (RefSeq)
chimpanzee ISOC1 471622 (Entrez Gene)
Chr5 XP_001160234 (RefSeq)
cattle ISOC1 540524 (Entrez Gene)
Chr7 A6QLY4 (UniProt | EBI)
NM_001101213 (RefSeq)
dog ISOC1 100688371 (Entrez Gene)
Chr11 XP_003431639 (RefSeq)
chicken ISOC1 415601 (Entrez Gene)
ChrZ XP_413969 (RefSeq)
zebrafish isoc1 559897 (Entrez Gene)
Chr10 Q08C33 (UniProt | EBI)
NM_001079981 (RefSeq)
frog, western clawed isoc1 780052 (Entrez Gene)
Chr1 Q0IHU5 (UniProt | EBI)
NM_001079129 (RefSeq)
macaque, rhesus ISOC1 705231 (Entrez Gene)
Chr6 NP_001253366 (RefSeq)
NM_001266437 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory