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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LDLRAP1 HGNC:18640 (HGNC)
26119 (Entrez Gene)
605747 (OMIM)
HGNC homology
Chr1 p36.11 Chr1:25543580-25590400 (+)
autosomal recessive hypercholesterolemia
Q5SW96 (UniProt | EBI)
NM_015627 (RefSeq)
mouse Ldlrap1 MGI:2140175 (MGI)
100017 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 67.09 cM Chr4:134741554-134768024 (-)
autosomal recessive hypercholesterolemia
OTTMUSG00000011121 (VEGA)
OTTMUSP00000011915 (VEGA)
OTTMUST00000026035 (VEGA)
rat Ldlrap1 500564 (Entrez Gene)
Chr5 q36 D3ZAR1 (UniProt | EBI)
NM_001109271 (RefSeq)
chimpanzee LDLRAP1 739347 (Entrez Gene)
cattle LDLRAP1 511199 (Entrez Gene)
Chr2 NP_001077137 (RefSeq)
NM_001083668 (RefSeq)
dog LDLRAP1 612219 (Entrez Gene)
Chr2 XP_005617840 (RefSeq)
chicken LDLRAP1 419589 (Entrez Gene)
Chr23 XP_015153218 (RefSeq)
zebrafish ldlrap1b 791153 (Entrez Gene)
Chr13 NP_001074104 (RefSeq)
NM_001080635 (RefSeq)
frog, western clawed ldlrap1 549868 (Entrez Gene)
Chr2 NP_001017114 (RefSeq)
NM_001017114 (RefSeq)
macaque, rhesus LDLRAP1 713032 (Entrez Gene)
Chr1 XP_001107620 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory