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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ENG HGNC:3349 (HGNC)
2022 (Entrez Gene)
131195 (OMIM)
Endoglin (MyGene.info)
HGNC homology
Chr9 q34.11 Chr9:127815012-127854773 (-)
hereditary hemorrhagic telangiectasia
P17813 (UniProt | EBI)
NM_001278138 (RefSeq)
mouse Eng MGI:95392 (MGI)
13805 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 22.09 cM Chr2:32646595-32682669 (+)
arteriovenous malformations of the brain
hereditary hemorrhagic telangiectasia
13805 (NCBI Gene Model)
Q63961 (UniProt | EBI)
NM_001146350 (RefSeq)
rat Eng 497010 (Entrez Gene)
Chr3 NP_001010968 (RefSeq)
NM_001010968 (RefSeq)
chimpanzee ENG 741046 (Entrez Gene)
Chr9 XP_016817213 (RefSeq)
cattle ENG 615844 (Entrez Gene)
Chr11 NP_001069865 (RefSeq)
NM_001076397 (RefSeq)
dog ENG 609166 (Entrez Gene)
Chr9 XP_005625387 (RefSeq)
chicken ENG 771557 (Entrez Gene)
Chr17 NP_001074356 (RefSeq)
NM_001080887 (RefSeq)
frog, western clawed eng 100491276 (Entrez Gene)
Chr8 XP_012824989 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory