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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
91153

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MLH3 HGNC:7128 (HGNC)
27030 (Entrez Gene)
604395 (OMIM)
Chr14 q24.3 Chr14:75013764-75051532 (-)
GRCh38
Colorectal Cancer, Hereditary Nonpolyposis, Type 7; HNPCC7
Endometrial Cancer
Q9UHC1 (UniProt | EBI)
NM_014381 (RefSeq)
mouse Mlh3 MGI:1353455 (MGI)
217716 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 39.61 cM Chr12:85234520-85270564 (-)
GRCm38
217716 (NCBI Gene Model)
NP_780546 (RefSeq)
NM_175337 (RefSeq)
rat Mlh3 314320 (Entrez Gene)
Chr6 q31 NP_001101513 (RefSeq)
NM_001108043 (RefSeq)
chimpanzee MLH3 453043 (Entrez Gene)
Chr14 XP_001158557 (RefSeq)
rhesus macaque MLH3 701482 (Entrez Gene)
Chr7 NP_001244712 (RefSeq)
NM_001257783 (RefSeq)
cattle MLH3 786279 (Entrez Gene)
Chr10 XP_003582790 (RefSeq)
dog MLH3 480389 (Entrez Gene)
Chr8 XP_537511 (RefSeq)
chicken MLH3 100859200 (Entrez Gene)
Chr5 XP_003641348 (RefSeq)
western clawed frog mlh3 100493832 (Entrez Gene)
ChrUN NP_001238771 (RefSeq)
NM_001251842 (RefSeq)
zebrafish mlh3 568323 (Entrez Gene)
Chr23 XP_696739 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory