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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DNM2 HGNC:2974 (HGNC)
1785 (Entrez Gene)
602378 (OMIM)
DNM2 (MyGene.info)
HGNC homology
Chr19 p13.2 Chr19:10718053-10831910 (+)
centronuclear myopathy
Charcot-Marie-Tooth disease dominant intermediate B
P50570 (UniProt | EBI)
NM_004945 (RefSeq)
mouse Dnm2 MGI:109547 (MGI)
13430 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 7.79 cM Chr9:21424908-21507759 (+)
centronuclear myopathy
cystic kidney disease
OTTMUSG00000038087 (VEGA)
OTTMUSP00000055080 (VEGA)
OTTMUST00000098121 (VEGA)
rat Dnm2 25751 (Entrez Gene)
Chr8 q13 P39052 (UniProt | EBI)
NM_013199 (RefSeq)
chimpanzee DNM2 455718 (Entrez Gene)
Chr19 XP_016790508 (RefSeq)
cattle DNM2 511691 (Entrez Gene)
Chr7 A6H7I5 (UniProt | EBI)
NM_001099369 (RefSeq)
dog DNM2 484949 (Entrez Gene)
Chr20 XP_005632944 (RefSeq)
zebrafish dnm2b 406525 (Entrez Gene)
Chr1 NP_998407 (RefSeq)
NM_213242 (RefSeq)
frog, western clawed dnm2 496487 (Entrez Gene)
Chr3 NP_001011076 (RefSeq)
NM_001011076 (RefSeq)
macaque, rhesus DNM2 713558 (Entrez Gene)
Chr19 NP_001252641 (RefSeq)
NM_001265712 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory