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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ARHGEF12 HGNC:14193 (HGNC)
23365 (Entrez Gene)
604763 (OMIM)
ARHGEF12 (MyGene.info)
HGNC homology
Chr11 q23.3 Chr11:120336276-120489936 (+)
Q9NZN5 (UniProt | EBI)
NM_001198665 (RefSeq)
mouse Arhgef12 MGI:1916882 (MGI)
69632 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 24.14 cM Chr9:42963842-43105718 (-)
69632 (NCBI Gene Model)
Q8R4H2 (UniProt | EBI)
NM_027144 (RefSeq)
rat Arhgef12 367072 (Entrez Gene)
Chr8 q22 NP_001013264 (RefSeq)
NM_001013246 (RefSeq)
chimpanzee ARHGEF12 451618 (Entrez Gene)
Chr11 XP_016777647 (RefSeq)
cattle ARHGEF12 503575 (Entrez Gene)
Chr7 NP_001116505 (RefSeq)
NM_001123033 (RefSeq)
dog ARHGEF12 479409 (Entrez Gene)
Chr5 XP_022273899 (RefSeq)
chicken ARHGEF12 419752 (Entrez Gene)
Chr24 XP_015153669 (RefSeq)
zebrafish arhgef12a 562455 (Entrez Gene)
Chr15 XP_009290007 (RefSeq)
arhgef12b 571031 (Entrez Gene)
Chr5 XP_009300161 (RefSeq)
frog, western clawed arhgef12 779951 (Entrez Gene)
Chr7 NP_001072496 (RefSeq)
NM_001079028 (RefSeq)
macaque, rhesus ARHGEF12 712096 (Entrez Gene)
Chr14 XP_028689913 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory