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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
8915

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MFN2 HGNC:16877 (HGNC)
9927 (Entrez Gene)
608507 (OMIM)
Chr1 p36.22 Chr1:11980181-12013515 (+)
GRCh38
Charcot-Marie-Tooth Disease, Axonal, Type 2A2; CMT2A2
Neuropathy, Hereditary Motor and Sensory, Type VI; HSMN6
O95140 (UniProt | EBI)
NM_014874 (RefSeq)
mouse Mfn2 MGI:2442230 (MGI)
170731 (Entrez Gene)
Gene Tree
VISTA-Point
Chr4 78.56 cM Chr4:147873599-147904704 (-)
GRCm38
Parkinson Disease, Late-Onset; PD
OTTMUSG00000010659 (VEGA)
OTTMUSP00000011419 (VEGA)
OTTMUST00000024886 (VEGA)
rat LOC100911485 100911485 (Entrez Gene)
Chr5 XP_003750134 (RefSeq)
Mfn2 64476 (Entrez Gene)
Chr5 q36 Q8R500 (UniProt | EBI)
NM_130894 (RefSeq)
chimpanzee MFN2 457958 (Entrez Gene)
Chr1 XP_514395 (RefSeq)
rhesus macaque MFN2 100427191 (Entrez Gene)
Chr1 XP_002802232 (RefSeq)
cattle MFN2 534574 (Entrez Gene)
Chr16 NP_001177198 (RefSeq)
NM_001190269 (RefSeq)
dog MFN2 487439 (Entrez Gene)
Chr2 NP_001271370 (RefSeq)
NM_001284441 (RefSeq)
chicken MFN2 419484 (Entrez Gene)
Chr21 XP_417640 (RefSeq)
zebrafish mfn2 567448 (Entrez Gene)
Chr8 NP_001121726 (RefSeq)
NM_001128254 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory