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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EDNRB HGNC:3180 (HGNC)
1910 (Entrez Gene)
131244 (OMIM)
HGNC homology
Chr13 q22 Chr13:77895481-77975529 (-)
Abcd Syndrome; ABCDS
Hirschsprung Disease, Susceptibility to, 2; HSCR2
Waardenburg Syndrome, Type 4A; WS4A
P24530 (UniProt | EBI)
NM_003991 (RefSeq)
mouse Ednrb MGI:102720 (MGI)
13618 (Entrez Gene)
Gene Tree
Chr14 53.05 cM Chr14:103814625-103844173 (-)
Hirschsprung Disease, Susceptibility to, 2; HSCR2
Waardenburg Syndrome, Type 4A; WS4A
ENSMUSG00000022122 (Ensembl Gene Model)
ENSMUSP00000022718 (Ensembl)
ENSMUST00000022718 (Ensembl)
rat Ednrb 50672 (Entrez Gene)
Chr15 q21-q22 P21451 (UniProt | EBI)
NM_017333 (RefSeq)
chimpanzee EDNRB 452613 (Entrez Gene)
Chr13 XP_509693 (RefSeq)
rhesus macaque EDNRB 697329 (Entrez Gene)
Chr17 XP_001089047 (RefSeq)
cattle EDNRB 281750 (Entrez Gene)
Chr12 q22 P28088 (UniProt | EBI)
NM_174309 (RefSeq)
dog EDNRB 403862 (Entrez Gene)
Chr22 P56497 (UniProt | EBI)
NM_001010943 (RefSeq)
chicken EDNRB 408082 (Entrez Gene)
Chr1 NP_001001127 (RefSeq)
NM_001001127 (RefSeq)
western clawed frog ednrb 779931 (Entrez Gene)
ChrUN NP_001072476 (RefSeq)
NM_001079008 (RefSeq)
zebrafish ednrba 30442 (Entrez Gene)
Chr1 NP_571272 (RefSeq)
NM_131197 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory