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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLEKHM1 HGNC:29017 (HGNC)
9842 (Entrez Gene)
611466 (OMIM)
PLEKHM1 (MyGene.info)
HGNC homology
Chr17 q21.31 Chr17:45434262-45490780 (-)
autosomal recessive osteopetrosis 6
Q9Y4G2 (UniProt | EBI)
NM_014798 (RefSeq)
mouse Plekhm1 MGI:2443207 (MGI)
353047 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 67.09 cM Chr11:103364275-103412687 (-)
autosomal recessive osteopetrosis 6
OTTMUSG00000002841 (VEGA)
OTTMUSP00000002735 (VEGA)
OTTMUST00000005762 (VEGA)
rat Plekhm1 303584 (Entrez Gene)
Chr10 q32.1 Q5PQS0 (UniProt | EBI)
NM_001009677 (RefSeq)
chimpanzee PLEKHM1 454754 (Entrez Gene)
Chr17 XP_016787078 (RefSeq)
cattle PLEKHM1 523424 (Entrez Gene)
Chr19 XP_024836705 (RefSeq)
chicken PLEKHM1 419939 (Entrez Gene)
Chr27 NP_001026095 (RefSeq)
NM_001030924 (RefSeq)
zebrafish plekhm1 564048 (Entrez Gene)
Chr12 NP_001314781 (RefSeq)
NM_001327851 (RefSeq)
frog, western clawed plekhm1 100491541 (Entrez Gene)
Chr10 XP_002933223 (RefSeq)
macaque, rhesus PLEKHM1 716464 (Entrez Gene)
Chr16 XP_014975401 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory