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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IST1 HGNC:28977 (HGNC)
9798 (Entrez Gene)
616434 (OMIM)
KIAA0174 (MyGene.info)
HGNC homology
Chr16 q22.2 Chr16:71894408-71930639 (+)
P53990 (UniProt | EBI)
NM_001270978 (RefSeq)
mouse Ist1 MGI:1919205 (MGI)
71955 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 57.18 cM Chr8:109671325-109693260 (-)
ENSMUSG00000031729 (Ensembl Gene Model)
ENSMUSP00000034164 (Ensembl)
ENSMUST00000034164 (Ensembl)
rat Ist1 307833 (Entrez Gene)
Chr19 q12 Q568Z6 (UniProt | EBI)
NM_001017454 (RefSeq)
chimpanzee IST1 745404 (Entrez Gene)
Chr16 NP_001267311 (RefSeq)
NM_001280382 (RefSeq)
cattle IST1 508900 (Entrez Gene)
Chr18 Q3ZBV1 (UniProt | EBI)
NM_001034335 (RefSeq)
dog IST1 479667 (Entrez Gene)
Chr5 XP_536798 (RefSeq)
chicken IST1 415877 (Entrez Gene)
Chr11 XP_025010120 (RefSeq)
zebrafish ist1 321460 (Entrez Gene)
Chr7 NP_997750 (RefSeq)
NM_212585 (RefSeq)
frog, western clawed ist1 100124797 (Entrez Gene)
Chr4 NP_001096241 (RefSeq)
NM_001102771 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory