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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
88330

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HFE HGNC:4886 (HGNC)
3077 (Entrez Gene)
613609 (OMIM)
Chr6 p21.3 Chr6:26087281-26096117 (+)
GRCh38
Alzheimer Disease; AD
Hemochromatosis, Type 1; HFE1
Microvascular Complications of Diabetes, Susceptibility to, 7; MVCD7
Porphyria Cutanea Tarda
Porphyria Variegata
Q30201 (UniProt | EBI)
NM_000410 (RefSeq)
mouse Hfe MGI:109191 (MGI)
15216 (Entrez Gene)
Gene Tree
VISTA-Point
Chr13 9.88 cM Chr13:23702034-23710854 (-)
GRCm38
Hemochromatosis, Type 1; HFE1
OTTMUSG00000000737 (VEGA)
OTTMUSP00000000659 (VEGA)
OTTMUST00000001384 (VEGA)
rat Hfe 29199 (Entrez Gene)
Chr17 p11-q11 O35799 (UniProt | EBI)
NM_053301 (RefSeq)
chimpanzee HFE 462489 (Entrez Gene)
Chr6 P60018 (UniProt | EBI)
NM_001009101 (RefSeq)
rhesus macaque HFE 696129 (Entrez Gene)
Chr4 NP_001247505 (RefSeq)
NM_001260576 (RefSeq)
cattle hfe 497622 (Entrez Gene)
Chr23 NP_001012399 (RefSeq)
NM_001012399 (RefSeq)
dog HFE 100688951 (Entrez Gene)
Chr35 XP_003434224 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory