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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ADAM10 HGNC:188 (HGNC)
102 (Entrez Gene)
602192 (OMIM)
ADAM10 (MyGene.info)
HGNC homology
Chr15 q21.3 Chr15:58595204-58749978 (-)
Alzheimer's disease 18
reticulate acropigmentation of Kitamura
O14672 (UniProt | EBI)
NM_001110 (RefSeq)
mouse Adam10 MGI:109548 (MGI)
11487 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 39.53 cM Chr9:70678997-70780229 (+)
ENSMUSG00000054693 (Ensembl Gene Model)
ENSMUSP00000063839 (Ensembl)
ENSMUST00000067880 (Ensembl)
rat Adam10 29650 (Entrez Gene)
Chr8 q24 Q10743 (UniProt | EBI)
NM_019254 (RefSeq)
chimpanzee ADAM10 746942 (Entrez Gene)
Chr15 XP_016783776 (RefSeq)
cattle ADAM10 282132 (Entrez Gene)
Chr10 Q10741 (UniProt | EBI)
NM_174496 (RefSeq)
dog ADAM10 478321 (Entrez Gene)
Chr30 XP_022268233 (RefSeq)
chicken ADAM10 374113 (Entrez Gene)
Chr10 NP_989592 (RefSeq)
NM_204261 (RefSeq)
zebrafish adam10a 566044 (Entrez Gene)
Chr7 NP_001152786 (RefSeq)
NM_001159314 (RefSeq)
frog, western clawed adam10 733451 (Entrez Gene)
Chr3 NP_001037869 (RefSeq)
NM_001044404 (RefSeq)
macaque, rhesus ADAM10 701355 (Entrez Gene)
Chr7 XP_028706819 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory