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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
863

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACVR2B HGNC:174 (HGNC)
93 (Entrez Gene)
602730 (OMIM)
Chr3 p22 Chr3:38454299-38493142 (+)
GRCh38
Heterotaxy, Visceral, 4, Autosomal; HTX4
Q13705 (UniProt | EBI)
NM_001106 (RefSeq)
mouse Acvr2b MGI:87912 (MGI)
11481 (Entrez Gene)
Gene Tree
VISTA-Point
Chr9 71.33 cM Chr9:119402501-119433515 (+)
GRCm38
Heterotaxy, Visceral, 4, Autosomal; HTX4
Right Atrial Isomerism; RAI
11481 (NCBI Gene Model)
P27040 (UniProt | EBI)
NM_007397 (RefSeq)
rat Acvr2b 25366 (Entrez Gene)
Chr8 q32 P38445 (UniProt | EBI)
NM_031554 (RefSeq)
chimpanzee ACVR2B 460271 (Entrez Gene)
Chr3 XP_516369 (RefSeq)
rhesus macaque ACVR2B 696071 (Entrez Gene)
Chr2 XP_001084713 (RefSeq)
cattle ACVR2B 282131 (Entrez Gene)
Chr22 Q95126 (UniProt | EBI)
NM_174495 (RefSeq)
dog ACVR2B 485590 (Entrez Gene)
Chr23 XP_542709 (RefSeq)
chicken ACVR2B 374213 (Entrez Gene)
Chr2 Q90670 (UniProt | EBI)
NM_204317 (RefSeq)
western clawed frog acvr2b 448641 (Entrez Gene)
ChrUN NP_001006871 (RefSeq)
NM_001006870 (RefSeq)
zebrafish acvr2b 30457 (Entrez Gene)
Chr24 NP_571285 (RefSeq)
NM_131210 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory