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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KCNQ1 HGNC:6294 (HGNC)
3784 (Entrez Gene)
607542 (OMIM)
KvLQT1 (MyGene.info)
HGNC homology
Chr11 p15.5-p15.4 Chr11:2444991-2849110 (+)
Beckwith-Wiedemann syndrome
familial atrial fibrillation
Jervell-Lange Nielsen syndrome
long QT syndrome 1
short QT syndrome
P51787 (UniProt | EBI)
NM_181798 (RefSeq)
mouse Kcnq1 MGI:108083 (MGI)
16535 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 88.12 cM Chr7:143106362-143427042 (+)
Jervell-Lange Nielsen syndrome
long QT syndrome 1
OTTMUSG00000046376 (VEGA)
OTTMUSP00000066799 (VEGA)
OTTMUST00000120842 (VEGA)
rat Kcnq1 84020 (Entrez Gene)
Chr1 q42 Q9Z0N7 (UniProt | EBI)
NM_032073 (RefSeq)
chimpanzee KCNQ1 450957 (Entrez Gene)
Chr11 XP_016775680 (RefSeq)
cattle KCNQ1 784876 (Entrez Gene)
Chr29 NP_001192370 (RefSeq)
NM_001205441 (RefSeq)
dog KCNQ1 483669 (Entrez Gene)
Chr18 XP_022260829 (RefSeq)
chicken KCNQ1 423090 (Entrez Gene)
Chr5 XP_421022 (RefSeq)
zebrafish kcnq1 557498 (Entrez Gene)
Chr7 NP_001116714 (RefSeq)
NM_001123242 (RefSeq)
frog, western clawed kcnq1 100145329 (Entrez Gene)
Chr4 XP_002936545 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory