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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SYNGAP1 HGNC:11497 (HGNC)
8831 (Entrez Gene)
603384 (OMIM)
SYNGAP1 (MyGene.info)
HGNC homology
Chr6 p21.32 Chr6:33420070-33453689 (+)
autosomal dominant non-syndromic intellectual disability 5
Q96PV0 (UniProt | EBI)
NM_001130066 (RefSeq)
mouse Syngap1 MGI:3039785 (MGI)
240057 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 13.6 cM Chr17:26941253-26972434 (+)
OTTMUSG00000049838 (VEGA)
OTTMUSP00000068605 (VEGA)
OTTMUST00000126931 (VEGA)
rat Syngap1 192117 (Entrez Gene)
Chr20 p12 Q9QUH6 (UniProt | EBI)
NM_181092 (RefSeq)
chimpanzee ZBTB9 746276 (Entrez Gene)
Chr6 XP_003950850 (RefSeq)
cattle SYNGAP1 790307 (Entrez Gene)
Chr23 NP_001192395 (RefSeq)
NM_001205466 (RefSeq)
dog SYNGAP1 481742 (Entrez Gene)
Chr12 XP_013973719 (RefSeq)
zebrafish syngap1a 100034485 (Entrez Gene)
Chr19 XP_005159375 (RefSeq)
syngap1b 100151149 (Entrez Gene)
Chr16 NP_001313396 (RefSeq)
NM_001326467 (RefSeq)
frog, western clawed syngap1 100038210 (Entrez Gene)
Chr8 XP_017952224 (RefSeq)
NM_001134816 (RefSeq)
macaque, rhesus SYNGAP1 717858 (Entrez Gene)
Chr4 XP_014991598 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory