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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NEK8 HGNC:13387 (HGNC)
284086 (Entrez Gene)
609799 (OMIM)
NEK8 (MyGene.info)
HGNC homology
Chr17 q11.2 Chr17:28727899-28743457 (+)
nephronophthisis 9
renal-hepatic-pancreatic dysplasia
Q86SG6 (UniProt | EBI)
NM_178170 (RefSeq)
mouse Nek8 MGI:1890646 (MGI)
140859 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 46.74 cM Chr11:78166106-78176675 (-)
autosomal recessive polycystic kidney disease
OTTMUSG00000000109 (VEGA)
OTTMUSP00000000162 (VEGA)
OTTMUST00000000369 (VEGA)
rat Nek8 287473 (Entrez Gene)
Chr10 q25 D3ZGQ5 (UniProt | EBI)
NM_001105804 (RefSeq)
chimpanzee NEK8 455033 (Entrez Gene)
Chr17 XP_016787652 (RefSeq)
cattle NEK8 532332 (Entrez Gene)
Chr19 NP_001179652 (RefSeq)
NM_001192723 (RefSeq)
dog NEK8 491171 (Entrez Gene)
Chr9 XP_022279055 (RefSeq)
chicken NEK8 417576 (Entrez Gene)
Chr19 XP_415822 (RefSeq)
zebrafish nek8 171094 (Entrez Gene)
Chr15 Q90XC2 (UniProt | EBI)
NM_139077 (RefSeq)
frog, western clawed nek8 448753 (Entrez Gene)
Chr2 NP_001006906 (RefSeq)
NM_001006905 (RefSeq)
macaque, rhesus NEK8 716323 (Entrez Gene)
Chr16 XP_014974416 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory