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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
8417

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NODAL HGNC:7865 (HGNC)
4838 (Entrez Gene)
601265 (OMIM)
Chr10 q22.1 Chr10:70431936-70441709 (-)
GRCh38
Heterotaxy, Visceral, 5, Autosomal; HTX5
Holoprosencephaly 1; HPE1
Q96S42 (UniProt | EBI)
NM_018055 (RefSeq)
mouse Nodal MGI:97359 (MGI)
18119 (Entrez Gene)
Gene Tree
VISTA-Point
Chr10 32.21 cM Chr10:61417972-61425338 (+)
GRCm38
OTTMUSG00000021483 (VEGA)
OTTMUSP00000023886 (VEGA)
OTTMUST00000050919 (VEGA)
rat Nodal 294503 (Entrez Gene)
Chr20 q11 NP_001099864 (RefSeq)
NM_001106394 (RefSeq)
chimpanzee NODAL 466100 (Entrez Gene)
Chr10 XP_521502 (RefSeq)
rhesus macaque NODAL 710424 (Entrez Gene)
Chr9 XP_001108137 (RefSeq)
cattle NODAL 530748 (Entrez Gene)
Chr28 NP_001192911 (RefSeq)
NM_001205982 (RefSeq)
dog NODAL 489028 (Entrez Gene)
Chr4 XP_546146 (RefSeq)
chicken NODAL 395205 (Entrez Gene)
Chr22 XP_424385 (RefSeq)
western clawed frog LOC100497218 100497218 (Entrez Gene)
ChrUN XP_002936396 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory