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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ALDH5A1 HGNC:408 (HGNC)
7915 (Entrez Gene)
610045 (OMIM)
HGNC homology
Chr6 p22 Chr6:24494969-24537207 (+)
Succinic Semialdehyde Dehydrogenase Deficiency; SSADHD
P51649 (UniProt | EBI)
NM_170740 (RefSeq)
mouse Aldh5a1 MGI:2441982 (MGI)
214579 (Entrez Gene)
Gene Tree
Chr13 10.77 cM Chr13:24907579-24937661 (-)
Succinic Semialdehyde Dehydrogenase Deficiency; SSADHD
OTTMUSG00000000603 (VEGA)
OTTMUSP00000000561 (VEGA)
OTTMUST00000001200 (VEGA)
rat Aldh5a1 291133 (Entrez Gene)
Chr17 p11 P51650 (UniProt | EBI)
NM_022851 (RefSeq)
chimpanzee ALDH5A1 449515 (Entrez Gene)
Chr6 Q6A2H0 (UniProt | EBI)
NM_001008991 (RefSeq)
rhesus macaque ALDH5A1 707902 (Entrez Gene)
Chr4 XP_001101142 (RefSeq)
cattle ALDH5A1 532724 (Entrez Gene)
Chr23 NP_001179664 (RefSeq)
NM_001192735 (RefSeq)
dog ALDH5A1 488246 (Entrez Gene)
Chr35 XP_013966075 (RefSeq)
chicken ALDH5A1 420818 (Entrez Gene)
Chr2 XP_418909 (RefSeq)
western clawed frog aldh5a1 100216127 (Entrez Gene)
ChrUN NP_001135578 (RefSeq)
NM_001142106 (RefSeq)
zebrafish aldh5a1 565235 (Entrez Gene)
Chr16 NP_001103938 (RefSeq)
NM_001110468 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory