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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DROSHA HGNC:17904 (HGNC)
29102 (Entrez Gene)
608828 (OMIM)
RNASEN (MyGene.info)
HGNC homology
Chr5 p13.3 Chr5:31400494-31532175 (-)
Q9NRR4 (UniProt | EBI)
NM_001100412 (RefSeq)
mouse Drosha MGI:1261425 (MGI)
14000 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 5.99 cM Chr15:12824815-12935291 (+)
ENSMUSG00000022191 (Ensembl Gene Model)
ENSMUSP00000087762 (Ensembl)
ENSMUST00000090292 (Ensembl)
rat Drosha 310159 (Entrez Gene)
Chr2 q16 NP_001101125 (RefSeq)
NM_001107655 (RefSeq)
chimpanzee DROSHA 471576 (Entrez Gene)
Chr5 XP_009447633 (RefSeq)
cattle DROSHA 540168 (Entrez Gene)
Chr20 XP_005221687 (RefSeq)
dog DROSHA 479375 (Entrez Gene)
chicken DROSHA 420911 (Entrez Gene)
Chr2 NP_001006379 (RefSeq)
NM_001006379 (RefSeq)
zebrafish drosha 567505 (Entrez Gene)
Chr12 NP_001103942 (RefSeq)
NM_001110472 (RefSeq)
frog, western clawed drosha 100135003 (Entrez Gene)
Chr6 NP_001107152 (RefSeq)
NM_001113680 (RefSeq)
macaque, rhesus DROSHA 692081 (Entrez Gene)
Chr6 NP_001248086 (RefSeq)
NM_001261157 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory