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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
817

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SLC6A4 HGNC:11050 (HGNC)
6532 (Entrez Gene)
182138 (OMIM)
Chr17 q11.2 Chr17:30194319-30235968 (-)
GRCh38
Anxiety
Obsessive-Compulsive Disorder; OCD
P31645 (UniProt | EBI)
NM_001045 (RefSeq)
mouse Slc6a4 MGI:96285 (MGI)
15567 (Entrez Gene)
Gene Tree
VISTA-Point
Chr11 46.18 cM Chr11:76998603-77032340 (+)
GRCm38
Autism
OTTMUSG00000006240 (VEGA)
OTTMUSP00000006548 (VEGA)
OTTMUST00000014089 (VEGA)
rat Slc6a4 25553 (Entrez Gene)
Chr10 q26 P31652 (UniProt | EBI)
NM_013034 (RefSeq)
chimpanzee SLC6A4 468201 (Entrez Gene)
Chr17 XP_001135066 (RefSeq)
rhesus macaque SLC6A4 574140 (Entrez Gene)
Chr16 Q9MYX0 (UniProt | EBI)
NM_001032823 (RefSeq)
cattle SLC6A4 282365 (Entrez Gene)
Chr19 Q9XT49 (UniProt | EBI)
NM_174609 (RefSeq)
dog SLC6A4 491184 (Entrez Gene)
Chr9 NP_001104241 (RefSeq)
NM_001110771 (RefSeq)
chicken SLC6A4 404747 (Entrez Gene)
Chr19 NP_998737 (RefSeq)
NM_213572 (RefSeq)
western clawed frog LOC100493853 100493853 (Entrez Gene)
ChrUN XP_002943421 (RefSeq)
zebrafish slc6a4a 664719 (Entrez Gene)
Chr15 NP_001035061 (RefSeq)
NM_001039972 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory