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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SLC6A4 HGNC:11050 (HGNC)
6532 (Entrez Gene)
182138 (OMIM)
Serotonin transporter (MyGene.info)
HGNC homology
Chr17 q11.2 Chr17:30194319-30235968 (-)
anxiety disorder
P31645 (UniProt | EBI)
NM_001045 (RefSeq)
mouse Slc6a4 MGI:96285 (MGI)
15567 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 46.18 cM Chr11:76998603-77032340 (+)
autistic disorder
sudden infant death syndrome
OTTMUSG00000006240 (VEGA)
OTTMUSP00000006550 (VEGA)
OTTMUST00000014091 (VEGA)
rat Slc6a4 25553 (Entrez Gene)
Chr10 q24 P31652 (UniProt | EBI)
NM_013034 (RefSeq)
chimpanzee SLC6A4 468201 (Entrez Gene)
Chr17 XP_001135066 (RefSeq)
cattle SLC6A4 282365 (Entrez Gene)
Chr19 Q9XT49 (UniProt | EBI)
NM_174609 (RefSeq)
dog SLC6A4 491184 (Entrez Gene)
Chr9 NP_001104241 (RefSeq)
NM_001110771 (RefSeq)
chicken SLC6A4 404747 (Entrez Gene)
Chr19 NP_998737 (RefSeq)
NM_213572 (RefSeq)
zebrafish slc6a4a 664719 (Entrez Gene)
Chr15 NP_001035061 (RefSeq)
NM_001039972 (RefSeq)
frog, western clawed slc6a4 100493853 (Entrez Gene)
Chr2 XP_017946918 (RefSeq)
macaque, rhesus SLC6A4 574140 (Entrez Gene)
Chr16 Q9MYX0 (UniProt | EBI)
NM_001032823 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory