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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SCNN1A HGNC:10599 (HGNC)
6337 (Entrez Gene)
600228 (OMIM)
Chr12 p13 Chr12:6346843-6377357 (-)
Bronchiectasis with or without Elevated Sweat Chloride 2; BESC2
Pseudohypoaldosteronism, Type I, Autosomal Recessive; PHA1B
P37088 (UniProt | EBI)
NM_001038 (RefSeq)
mouse Scnn1a MGI:101782 (MGI)
20276 (Entrez Gene)
Gene Tree
Chr6 59.32 cM Chr6:125320659-125344943 (+)
OTTMUSG00000038566 (VEGA)
OTTMUSP00000055834 (VEGA)
OTTMUST00000099477 (VEGA)
rat Scnn1a 25122 (Entrez Gene)
Chr4 q42 P37089 (UniProt | EBI)
NM_031548 (RefSeq)
chimpanzee SCNN1A 451776 (Entrez Gene)
Chr12 H2Q5A1 (UniProt | EBI)
rhesus macaque SCNN1A 712476 (Entrez Gene)
Chr11 XP_015006376 (RefSeq)
cattle SCNN1A 282348 (Entrez Gene)
Chr5 P55270 (UniProt | EBI)
NM_174598 (RefSeq)
dog SCNN1A 403650 (Entrez Gene)
Chr27 XP_005637311 (RefSeq)
chicken SCNN1A 396050 (Entrez Gene)
Chr1 Q92075 (UniProt | EBI)
NM_205145 (RefSeq)
western clawed frog scnn1a 395013 (Entrez Gene)
ChrUN NP_001184124 (RefSeq)
NM_001197195 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory