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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IRF5 HGNC:6120 (HGNC)
3663 (Entrez Gene)
607218 (OMIM)
IRF5 (MyGene.info)
HGNC homology
Chr7 q32.1 Chr7:128937737-128950042 (+)
inflammatory bowel disease 14
systemic lupus erythematosus
Q13568 (UniProt | EBI)
NM_001347928 (RefSeq)
mouse Irf5 MGI:1350924 (MGI)
27056 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 12.36 cM Chr6:29526625-29541871 (+)
OTTMUSG00000035855 (VEGA)
OTTMUSP00000050675 (VEGA)
OTTMUST00000091896 (VEGA)
rat Irf5 296953 (Entrez Gene)
Chr4 q22 NP_001100056 (RefSeq)
NM_001106586 (RefSeq)
chimpanzee IRF5 472512 (Entrez Gene)
Chr7 XP_001154689 (RefSeq)
cattle IRF5 615340 (Entrez Gene)
Chr4 Q58DJ0 (UniProt | EBI)
NM_001035465 (RefSeq)
dog IRF5 482264 (Entrez Gene)
Chr14 XP_005628465 (RefSeq)
chicken IRF5 430409 (Entrez Gene)
Chr1 NP_001026758 (RefSeq)
NM_001031587 (RefSeq)
macaque, rhesus IRF5 700725 (Entrez Gene)
Chr3 XP_014990365 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory