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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TYROBP HGNC:12449 (HGNC)
7305 (Entrez Gene)
604142 (OMIM)
HGNC homology
Chr19 q13.12 Chr19:35904401-35908309 (-)
Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy;
O43914 (UniProt | EBI)
NM_003332 (RefSeq)
mouse Tyrobp MGI:1277211 (MGI)
22177 (Entrez Gene)
Gene Tree
Chr7 17.45 cM Chr7:30413760-30417585 (+)
Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy;
OTTMUSG00000059315 (VEGA)
OTTMUSP00000075837 (VEGA)
OTTMUST00000145581 (VEGA)
rat Tyrobp 361537 (Entrez Gene)
Chr1 q21 Q6X9T7 (UniProt | EBI)
NM_212525 (RefSeq)
chimpanzee TYROBP 455968 (Entrez Gene)
Chr19 A4F4L0 (UniProt | EBI)
NM_001083623 (RefSeq)
rhesus macaque TYROBP 574207 (Entrez Gene)
Chr19 Q8WNQ8 (UniProt | EBI)
NM_001032867 (RefSeq)
cattle TYROBP 282390 (Entrez Gene)
Chr18 Q95J79 (UniProt | EBI)
NM_174627 (RefSeq)
dog TYROBP 476477 (Entrez Gene)
Chr1 NP_001184046 (RefSeq)
NM_001197117 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory