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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TREX1 HGNC:12269 (HGNC)
11277 (Entrez Gene)
606609 (OMIM)
TREX1 (MyGene.info)
HGNC homology
Chr3 p21.31 Chr3:48465520-48467645 (+)
Aicardi-Goutieres syndrome
Chilblain lupus
systemic lupus erythematosus
Q9NSU2 (UniProt | EBI)
NM_033628 (RefSeq)
mouse Trex1 MGI:1328317 (MGI)
22040 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 59.63 cM Chr9:109057933-109059734 (-)
Aicardi-Goutieres syndrome
cutaneous lupus erythematosus
OTTMUSG00000055468 (VEGA)
OTTMUSP00000022432 (VEGA)
OTTMUST00000048743 (VEGA)
rat Trex1 100049583 (Entrez Gene)
Chr8 NP_001020160 (RefSeq)
NM_001024989 (RefSeq)
chimpanzee TREX1 742742 (Entrez Gene)
Chr3 XP_024211226 (RefSeq)
cattle TREX1 282099 (Entrez Gene)
Chr22 Q9BG99 (UniProt | EBI)
NM_174475 (RefSeq)
dog TREX1 102155466 (Entrez Gene)
Chr20 XP_013977676 (RefSeq)
macaque, rhesus TREX1 100429168 (Entrez Gene)
Chr2 XP_002802855 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory