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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7982

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TREX1 HGNC:12269 (HGNC)
11277 (Entrez Gene)
606609 (OMIM)
Chr3 p21.31 Chr3:48465520-48467645 (+)
GRCh38
Aicardi-Goutieres Syndrome 1; AGS1
Chilblain Lupus 1; CHBL1
Systemic Lupus Erythematosus; SLE
Vasculopathy, Retinal, with Cerebral Leukodystrophy; RVCL
Q9NSU2 (UniProt | EBI)
NM_016381 (RefSeq)
mouse Trex1 MGI:1328317 (MGI)
22040 (Entrez Gene)
Gene Tree
VISTA-Point
Chr9 59.63 cM Chr9:109057933-109060338 (-)
GRCm38
Aicardi-Goutieres Syndrome 1; AGS1
OTTMUSG00000020568 (VEGA)
OTTMUSP00000022432 (VEGA)
OTTMUST00000048743 (VEGA)
rat Trex1 100049583 (Entrez Gene)
Chr8 NP_001020160 (RefSeq)
NM_001024989 (RefSeq)
chimpanzee TREX1 742742 (Entrez Gene)
Chr3 XP_003309834 (RefSeq)
rhesus macaque LOC100429168 100429168 (Entrez Gene)
Chr2 XP_002802855 (RefSeq)
dog TREX1 102155466 (Entrez Gene)
Chr20 XP_005632646 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory