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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7966

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TBX1 HGNC:11592 (HGNC)
6899 (Entrez Gene)
602054 (OMIM)
Chr22 q11.21 Chr22:19756703-19783593 (+)
GRCh38
Conotruncal Heart Malformations; CTHM
DiGeorge Syndrome; DGS
Tetralogy of Fallot; TOF
Velocardiofacial Syndrome
O43435 (UniProt | EBI)
NM_005992 (RefSeq)
mouse Tbx1 MGI:98493 (MGI)
21380 (Entrez Gene)
Gene Tree
VISTA-Point
Chr16 11.51 cM Chr16:18581713-18586969 (-)
GRCm38
Autism
DiGeorge Syndrome; DGS
Otitis Media, Susceptibility to
Velocardiofacial Syndrome
21380 (NCBI Gene Model)
P70323 (UniProt | EBI)
NM_001285472 (RefSeq)
rat Tbx1 360737 (Entrez Gene)
Chr11 q23 NP_001101792 (RefSeq)
NM_001108322 (RefSeq)
chimpanzee TBX1 458653 (Entrez Gene)
Chr22 XP_514982 (RefSeq)
rhesus macaque LOC100429202 100429202 (Entrez Gene)
Chr10 XP_002798308 (RefSeq)
dog TBX1 608214 (Entrez Gene)
Chr26 XP_850266 (RefSeq)
western clawed frog tbx1 619587 (Entrez Gene)
ChrUN Q3SA49 (UniProt | EBI)
NM_001035118 (RefSeq)
zebrafish tbx1 368206 (Entrez Gene)
Chr5 Q8AXX2 (UniProt | EBI)
NM_183339 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory