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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human STAT3 HGNC:11364 (HGNC)
6774 (Entrez Gene)
102582 (OMIM)
Chr17 q21.31 Chr17:42313324-42388568 (-)
Autoimmune Disease, Multisystem, Infantile-Onset; ADMIO
Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant
P40763 (UniProt | EBI)
NM_003150 (RefSeq)
mouse Stat3 MGI:103038 (MGI)
20848 (Entrez Gene)
Gene Tree
Chr11 63.82 cM Chr11:100885098-100939540 (-)
Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant
OTTMUSG00000002128 (VEGA)
OTTMUSP00000002052 (VEGA)
OTTMUST00000004321 (VEGA)
rat Stat3 25125 (Entrez Gene)
Chr10 q32.1 P52631 (UniProt | EBI)
NM_012747 (RefSeq)
chimpanzee STAT3 454682 (Entrez Gene)
Chr17 XP_001165274 (RefSeq)
rhesus macaque STAT3 574128 (Entrez Gene)
Chr16 XP_001109505 (RefSeq)
cattle STAT3 508541 (Entrez Gene)
Chr19 P61635 (UniProt | EBI)
NM_001012671 (RefSeq)
dog STAT3 490967 (Entrez Gene)
Chr9 XP_548090 (RefSeq)
chicken STAT3 420027 (Entrez Gene)
Chr27 Q6DV79 (UniProt | EBI)
NM_001030931 (RefSeq)
western clawed frog LOC100498278 100498278 (Entrez Gene)
ChrUN XP_002941970 (RefSeq)
zebrafish stat3 30767 (Entrez Gene)
Chr3 NP_571554 (RefSeq)
NM_131479 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory