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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SCN8A HGNC:10596 (HGNC)
6334 (Entrez Gene)
600702 (OMIM)
SCN8A (MyGene.info)
HGNC homology
Chr12 q13.13 Chr12:51589959-51812865 (+)
Ohtahara syndrome
Q9UQD0 (UniProt | EBI)
NM_001177984 (RefSeq)
mouse Scn8a MGI:103169 (MGI)
20273 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 56.39 cM Chr15:100869858-101045938 (+)
infantile epileptic encephalopathy
OTTMUSG00000055611 (VEGA)
OTTMUSP00000072461 (VEGA)
OTTMUST00000137635 (VEGA)
rat Scn8a 29710 (Entrez Gene)
Chr7 q36 O88420 (UniProt | EBI)
NM_019266 (RefSeq)
chimpanzee SCN8A 451906 (Entrez Gene)
Chr12 XP_016778854 (RefSeq)
cattle SCN8A 537277 (Entrez Gene)
Chr5 NP_001180031 (RefSeq)
NM_001193102 (RefSeq)
dog SCN8A 477604 (Entrez Gene)
Chr27 XP_022267231 (RefSeq)
chicken SCN8A 426869 (Entrez Gene)
Chr33 XP_015155743 (RefSeq)
zebrafish scn8aa 58152 (Entrez Gene)
Chr23 NP_571703 (RefSeq)
NM_131628 (RefSeq)
scn8ab 793996 (Entrez Gene)
Chr6 NP_001038648 (RefSeq)
NM_001045183 (RefSeq)
frog, western clawed LOC101731347 101731347 (Entrez Gene)
macaque, rhesus SCN8A 695972 (Entrez Gene)
Chr11 XP_015007232 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory