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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7904

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PRNP HGNC:9449 (HGNC)
5621 (Entrez Gene)
176640 (OMIM)
Chr20 p13 Chr20:4686151-4701588 (+)
GRCh38
Creutzfeldt-Jakob Disease; CJD
Fatal Familial Insomnia; FFI
Gerstmann-Straussler Disease; GSD
Huntington Disease-Like 1; HDL1
Kuru, Susceptibility to
Spongiform Encephalopathy with Neuropsychiatric Features
P04156 (UniProt | EBI)
NM_000311 (RefSeq)
mouse Prnp MGI:97769 (MGI)
19122 (Entrez Gene)
Gene Tree
VISTA-Point
Chr2 64.07 cM Chr2:131909928-131938429 (+)
GRCm38
Creutzfeldt-Jakob Disease; CJD
Fatal Familial Insomnia; FFI
OTTMUSG00000014846 (VEGA)
OTTMUSP00000015760 (VEGA)
OTTMUST00000035259 (VEGA)
rat Prnp 24686 (Entrez Gene)
Chr3 q36 P13852 (UniProt | EBI)
NM_012631 (RefSeq)
chimpanzee PRNP 458076 (Entrez Gene)
Chr20 P61768 (UniProt | EBI)
NM_001009093 (RefSeq)
rhesus macaque PRNP 717859 (Entrez Gene)
Chr10 P67997 (UniProt | EBI)
NM_001047152 (RefSeq)
cattle PRNP 281427 (Entrez Gene)
Chr13 q17 F7VJQ2 (UniProt | EBI)
NM_001271625 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory