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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PRNP HGNC:9449 (HGNC)
5621 (Entrez Gene)
176640 (OMIM)
PRNP (MyGene.info)
HGNC homology
Chr20 p13 Chr20:4686151-4701588 (+)
Creutzfeldt-Jakob disease
fatal familial insomnia
Gerstmann-Straussler-Scheinker syndrome
Huntington's disease-like 1
F7VJQ1 (UniProt | EBI)
NM_001080123 (RefSeq)
mouse Prnp MGI:97769 (MGI)
19122 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 64.07 cM Chr2:131909928-131938429 (+)
Creutzfeldt-Jakob disease
fatal familial insomnia
Gerstmann-Straussler-Scheinker syndrome
OTTMUSG00000014846 (VEGA)
OTTMUSP00000015760 (VEGA)
OTTMUST00000035259 (VEGA)
rat Prnp 24686 (Entrez Gene)
Chr3 q36 P13852 (UniProt | EBI)
NM_012631 (RefSeq)
chimpanzee PRNP 458076 (Entrez Gene)
Chr20 P61768 (UniProt | EBI)
NM_001110206 (RefSeq)
cattle PRNP 281427 (Entrez Gene)
Chr13 q17 P10279 (UniProt | EBI)
NM_181015 (RefSeq)
macaque, rhesus PRNP 717859 (Entrez Gene)
Chr10 P67997 (UniProt | EBI)
NM_001047152 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory