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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MPL HGNC:7217 (HGNC)
4352 (Entrez Gene)
159530 (OMIM)
Thrombopoietin receptor (MyGene.info)
HGNC homology
Chr1 p34.2 Chr1:43336875-43354464 (+)
congenital amegakaryocytic thrombocytopenia
essential thrombocythemia
P40238 (UniProt | EBI)
NM_005373 (RefSeq)
mouse Mpl MGI:97076 (MGI)
17480 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 54.61 cM Chr4:118442415-118457513 (-)
congenital amegakaryocytic thrombocytopenia
OTTMUSG00000008795 (VEGA)
OTTMUSP00000009174 (VEGA)
OTTMUST00000019997 (VEGA)
rat Mpl 366455 (Entrez Gene)
Chr5 q36 XP_017458567 (RefSeq)
cattle MPL 528492 (Entrez Gene)
Chr3 NP_001179592 (RefSeq)
NM_001192663 (RefSeq)
chicken MPL 414804 (Entrez Gene)
Chr8 NP_001001782 (RefSeq)
NM_001001782 (RefSeq)
zebrafish mpl 445381 (Entrez Gene)
Chr6 NP_001003858 (RefSeq)
NM_001003858 (RefSeq)
macaque, rhesus MPL 723813 (Entrez Gene)
Chr1 XP_014992943 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory