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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
7813

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LEF1 HGNC:6551 (HGNC)
51176 (Entrez Gene)
153245 (OMIM)
Chr4 q23-q25 Chr4:108047545-108168956 (-)
GRCh38
Lymphoid Enhancer-Binding Factor 1; LEF1
Q9UJU2 (UniProt | EBI)
NM_016269 (RefSeq)
mouse Lef1 MGI:96770 (MGI)
16842 (Entrez Gene)
Gene Tree
VISTA-Point
Chr3 60.78 cM Chr3:131110471-131224356 (+)
GRCm38
OTTMUSG00000020276 (VEGA)
OTTMUSP00000021970 (VEGA)
OTTMUST00000048123 (VEGA)
rat Lef1 161452 (Entrez Gene)
Chr2 q34-q45 Q9QXN1 (UniProt | EBI)
NM_130429 (RefSeq)
chimpanzee LEF1 461425 (Entrez Gene)
Chr4 XP_001136065 (RefSeq)
cattle LEF1 535399 (Entrez Gene)
Chr6 NP_001179785 (RefSeq)
NM_001192856 (RefSeq)
dog LEF1 478507 (Entrez Gene)
Chr32 XP_863334 (RefSeq)
chicken LEF1 395865 (Entrez Gene)
Chr4 NP_990344 (RefSeq)
NM_205013 (RefSeq)
zebrafish lef1 30701 (Entrez Gene)
Chr1 NP_571501 (RefSeq)
NM_131426 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory