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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LEF1 HGNC:6551 (HGNC)
51176 (Entrez Gene)
153245 (OMIM)
HGNC homology
Chr4 q25 Chr4:108047545-108168956 (-)
Q9UJU2 (UniProt | EBI)
NM_001130714 (RefSeq)
mouse Lef1 MGI:96770 (MGI)
16842 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 60.78 cM Chr3:131110471-131224356 (+)
OTTMUSG00000020276 (VEGA)
OTTMUSP00000021970 (VEGA)
OTTMUST00000048123 (VEGA)
rat Lef1 161452 (Entrez Gene)
Chr2 q43 Q9QXN1 (UniProt | EBI)
NM_130429 (RefSeq)
chimpanzee LEF1 461425 (Entrez Gene)
Chr4 XP_009446382 (RefSeq)
cattle LEF1 535399 (Entrez Gene)
Chr6 NP_001179785 (RefSeq)
NM_001192856 (RefSeq)
dog LEF1 478507 (Entrez Gene)
Chr32 XP_863377 (RefSeq)
chicken LEF1 395865 (Entrez Gene)
Chr4 NP_990344 (RefSeq)
NM_205013 (RefSeq)
zebrafish lef1 30701 (Entrez Gene)
Chr1 NP_571501 (RefSeq)
NM_131426 (RefSeq)
frog, western clawed lef1 100493178 (Entrez Gene)
Chr1 NP_001230763 (RefSeq)
NM_001243834 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory