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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CST3 HGNC:2475 (HGNC)
1471 (Entrez Gene)
604312 (OMIM)
Cystatin C (MyGene.info)
HGNC homology
Chr20 p11.21 Chr20:23627897-23638048 (-)
age related macular degeneration 11
CST3-related cerebral amyloid angiopathy
P01034 (UniProt | EBI)
NM_001288614 (RefSeq)
mouse Cst3 MGI:102519 (MGI)
13010 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 73.6 cM Chr2:148871722-148875692 (-)
OTTMUSG00000015724 (VEGA)
OTTMUSP00000016736 (VEGA)
OTTMUST00000037353 (VEGA)
rat Cst3 25307 (Entrez Gene)
Chr3 q41 P14841 (UniProt | EBI)
NM_012837 (RefSeq)
chimpanzee CST3 743081 (Entrez Gene)
Chr20 XP_016793041 (RefSeq)
cattle CST3 281102 (Entrez Gene)
Chr13 P01035 (UniProt | EBI)
NM_174029 (RefSeq)
dog LOC607874 607874 (Entrez Gene)
Chr23 XP_003639869 (RefSeq)
chicken CST3 396497 (Entrez Gene)
Chr3 P01038 (UniProt | EBI)
NM_205500 (RefSeq)
frog, western clawed LOC100485774 100485774 (Entrez Gene)
Chr5 XP_002934915 (RefSeq)
macaque, rhesus CST3 574313 (Entrez Gene)
Chr10 O19092 (UniProt | EBI)
NM_001032924 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory