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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FGF8 HGNC:3686 (HGNC)
2253 (Entrez Gene)
600483 (OMIM)
FGF8 (MyGene.info)
HGNC homology
Chr10 q24.32 Chr10:101770130-101780369 (-)
hypogonadotropic hypogonadism 6 with or without anosmia
P55075 (UniProt | EBI)
NM_033164 (RefSeq)
mouse Fgf8 MGI:99604 (MGI)
14179 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 38.75 cM Chr19:45736798-45742915 (-)
DiGeorge syndrome
tetralogy of Fallot
OTTMUSG00000021697 (VEGA)
OTTMUSP00000024240 (VEGA)
OTTMUST00000051481 (VEGA)
rat Fgf8 29349 (Entrez Gene)
Chr1 q54 NP_579820 (RefSeq)
NM_133286 (RefSeq)
cattle FGF8 326284 (Entrez Gene)
Chr26 NP_001193607 (RefSeq)
NM_001206678 (RefSeq)
chicken FGF8 396313 (Entrez Gene)
Chr6 Q90722 (UniProt | EBI)
NM_001012767 (RefSeq)
zebrafish fgf8a 30538 (Entrez Gene)
Chr13 O57341 (UniProt | EBI)
NM_131281 (RefSeq)
frog, western clawed fgf8 493525 (Entrez Gene)
Chr7 NP_001008163 (RefSeq)
NM_001008162 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory