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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TCF7L2 HGNC:11641 (HGNC)
6934 (Entrez Gene)
602228 (OMIM)
Chr10 q25.3 Chr10:112950219-113167678 (+)
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Q9NQB0 (UniProt | EBI)
NM_030756 (RefSeq)
mouse Tcf7l2 MGI:1202879 (MGI)
21416 (Entrez Gene)
Gene Tree
Chr19 51.59 cM Chr19:55741820-55933654 (+)
OTTMUSG00000020410 (VEGA)
OTTMUSP00000022201 (VEGA)
OTTMUST00000048437 (VEGA)
rat Tcf7l2 679869 (Entrez Gene)
Chr1 q55 NP_001177981 (RefSeq)
NM_001191052 (RefSeq)
chimpanzee TCF7L2 450743 (Entrez Gene)
Chr10 XP_009457529 (RefSeq)
rhesus macaque LOC701759 701759 (Entrez Gene)
Chr9 XP_001090054 (RefSeq)
dog TCF7L2 486894 (Entrez Gene)
Chr28 XP_005637793 (RefSeq)
chicken TCF7L2 395508 (Entrez Gene)
Chr6 NP_001193439 (RefSeq)
NM_001206510 (RefSeq)
western clawed frog tcf7l2 100101719 (Entrez Gene)
ChrUN NP_001231922 (RefSeq)
NM_001244993 (RefSeq)
zebrafish tcf7l2 30510 (Entrez Gene)
Chr12 NP_571334 (RefSeq)
NM_131259 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory