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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RET HGNC:9967 (HGNC)
5979 (Entrez Gene)
164761 (OMIM)
RET proto-oncogene (MyGene.info)
HGNC homology
Chr10 q11.21 Chr10:43077069-43130351 (+)
congenital central hypoventilation syndrome
familial medullary thyroid carcinoma
multiple endocrine neoplasia type 2A
multiple endocrine neoplasia type 2B
P07949 (UniProt | EBI)
NM_000323 (RefSeq)
mouse Ret MGI:97902 (MGI)
19713 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 55.86 cM Chr6:118151745-118197718 (-)
Hirschsprung's disease
multiple endocrine neoplasia type 2B
ENSMUSG00000030110 (Ensembl Gene Model)
ENSMUSP00000032201 (Ensembl)
ENSMUST00000032201 (Ensembl)
rat Ret 24716 (Entrez Gene)
Chr4 G3V9H8 (UniProt | EBI)
NM_012643 (RefSeq)
chimpanzee RET 100612888 (Entrez Gene)
Chr10 XP_016818564 (RefSeq)
cattle RET 515924 (Entrez Gene)
Chr28 NP_001178412 (RefSeq)
NM_001191483 (RefSeq)
dog RET 403494 (Entrez Gene)
Chr28 NP_001184028 (RefSeq)
NM_001197099 (RefSeq)
chicken RET 396107 (Entrez Gene)
Chr6 NP_990521 (RefSeq)
NM_205190 (RefSeq)
zebrafish ret 30512 (Entrez Gene)
Chr13 NP_858048 (RefSeq)
NM_181662 (RefSeq)
frog, western clawed ret 100495902 (Entrez Gene)
Chr7 XP_002933941 (RefSeq)
macaque, rhesus RET 703466 (Entrez Gene)
Chr9 XP_015002368 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory