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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7517

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RET HGNC:9967 (HGNC)
5979 (Entrez Gene)
164761 (OMIM)
Chr10 q11.2 Chr10:43077069-43130351 (+)
GRCh38
Central Hypoventilation Syndrome, Congenital; CCHS
Hirschsprung Disease, Susceptibility to, 1; HSCR1
Multiple Endocrine Neoplasia, Type IIA; MEN2A
Multiple Endocrine Neoplasia, Type IIB; MEN2B
Pheochromocytoma Pheochromocytoma, Susceptibility to
Rearranged During Transfection Protooncogene; RET
Renal Hypodysplasia/Aplasia 1; RHDA1
Thyroid Carcinoma, Familial Medullary; MTC
P07949 (UniProt | EBI)
NM_020630 (RefSeq)
mouse Ret MGI:97902 (MGI)
19713 (Entrez Gene)
Gene Tree
VISTA-Point
Chr6 55.86 cM Chr6:118151748-118197744 (-)
GRCm38
Clubfoot, Congenital, with or without Deficiency of Long Bones and/or Mirror-Image Polydactyly; CCF
Hirschsprung Disease, Susceptibility to, 1; HSCR1
Multiple Endocrine Neoplasia, Type IIB; MEN2B
Pheochromocytoma Pheochromocytoma, Susceptibility to
19713 (NCBI Gene Model)
P35546 (UniProt | EBI)
NM_001080780 (RefSeq)
rat Ret 24716 (Entrez Gene)
Chr4 G3V9H8 (UniProt | EBI)
NM_012643 (RefSeq)
chimpanzee RET 100612888 (Entrez Gene)
Chr10 XP_003312612 (RefSeq)
rhesus macaque RET 703466 (Entrez Gene)
Chr9 XP_002805672 (RefSeq)
cattle RET 515924 (Entrez Gene)
Chr28 NP_001178412 (RefSeq)
NM_001191483 (RefSeq)
dog RET 403494 (Entrez Gene)
Chr28 NP_001184028 (RefSeq)
NM_001197099 (RefSeq)
chicken RET 396107 (Entrez Gene)
Chr6 NP_990521 (RefSeq)
NM_205190 (RefSeq)
western clawed frog ret 100495902 (Entrez Gene)
ChrUN XP_002933941 (RefSeq)
zebrafish ret 30512 (Entrez Gene)
Chr13 NP_858048 (RefSeq)
NM_181662 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory