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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SHANK3 HGNC:14294 (HGNC)
85358 (Entrez Gene)
606230 (OMIM)
SHANK3 (MyGene.info)
HGNC homology
Chr22 q13.33 Chr22:50674642-50733212 (+)
schizophrenia 15
Q9BYB0 (UniProt | EBI)
NM_033517 (RefSeq)
mouse Shank3 MGI:1930016 (MGI)
58234 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 44.96 cM Chr15:89499623-89560261 (+)
autistic disorder
OTTMUSG00000024288 (VEGA)
OTTMUSP00000028933 (VEGA)
OTTMUST00000059483 (VEGA)
rat Shank3 59312 (Entrez Gene)
Chr7 q34 Q9JLU4 (UniProt | EBI)
NM_021676 (RefSeq)
chimpanzee SHANK3 100614904 (Entrez Gene)
Chr22 XP_016794998 (RefSeq)
cattle SHANK3 512428 (Entrez Gene)
Chr5 XP_024848661 (RefSeq)
dog SHANK3 474456 (Entrez Gene)
Chr10 XP_022280594 (RefSeq)
zebrafish shank3b 566152 (Entrez Gene)
Chr4 XP_009298458 (RefSeq)
frog, western clawed shank3 100488068 (Entrez Gene)
Chr3 XP_017947859 (RefSeq)
macaque, rhesus SHANK3 100430318 (Entrez Gene)
Chr10 XP_015006140 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory