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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
75163

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SHANK3 HGNC:14294 (HGNC)
85358 (Entrez Gene)
606230 (OMIM)
Chr22 q13.3 Chr22:50674642-50733212 (+)
GRCh38
Phelan-Mcdermid Syndrome
Schizophrenia 15; SCZD15
Q9BYB0 (UniProt | EBI)
NM_001080420 (RefSeq)
mouse Shank3 MGI:1930016 (MGI)
58234 (Entrez Gene)
Gene Tree
VISTA-Point
Chr15 44.96 cM Chr15:89499623-89560261 (+)
GRCm38
Autism
OTTMUSG00000024288 (VEGA)
OTTMUSP00000028933 (VEGA)
OTTMUST00000059483 (VEGA)
rat Shank3 59312 (Entrez Gene)
Chr7 q34 Q9JLU4 (UniProt | EBI)
NM_021676 (RefSeq)
chimpanzee SHANK3 100614904 (Entrez Gene)
Chr22 XP_003317380 (RefSeq)
rhesus macaque LOC100430318 100430318 (Entrez Gene)
Chr10 XP_002798472 (RefSeq)
cattle SHANK3 512428 (Entrez Gene)
Chr5 XP_589942 (RefSeq)
dog SHANK3 474456 (Entrez Gene)
Chr10 XP_005626259 (RefSeq)
western clawed frog shank3 100488068 (Entrez Gene)
ChrUN XP_002941881 (RefSeq)
zebrafish shank3b 566152 (Entrez Gene)
Chr4 XP_003198290 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory