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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7507

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RAG2 HGNC:9832 (HGNC)
5897 (Entrez Gene)
179616 (OMIM)
Chr11 p13 Chr11:36591943-36598279 (-)
GRCh38
Combined Cellular and Humoral Immune Defects with Granulomas; CCHIDG
Omenn Syndrome
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Positive
P55895 (UniProt | EBI)
NM_000536 (RefSeq)
mouse Rag2 MGI:97849 (MGI)
19374 (Entrez Gene)
Gene Tree
VISTA-Point
Chr2 53.87 cM Chr2:101624718-101632529 (+)
GRCm38
Omenn Syndrome
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Positive
OTTMUSG00000014585 (VEGA)
OTTMUSP00000015478 (VEGA)
OTTMUST00000034581 (VEGA)
rat Rag2 295953 (Entrez Gene)
Chr3 q31 NP_001093998 (RefSeq)
NM_001100528 (RefSeq)
chimpanzee RAG2 466490 (Entrez Gene)
Chr11 XP_001155150 (RefSeq)
rhesus macaque RAG2 716837 (Entrez Gene)
Chr14 XP_001114734 (RefSeq)
cattle RAG2 782387 (Entrez Gene)
Chr15 NP_001075938 (RefSeq)
NM_001082469 (RefSeq)
dog RAG2 483419 (Entrez Gene)
Chr18 XP_005631162 (RefSeq)
chicken RAG2 423165 (Entrez Gene)
Chr5 P25022 (UniProt | EBI)
western clawed frog rag2 100494391 (Entrez Gene)
ChrUN XP_002937337 (RefSeq)
zebrafish rag2 30658 (Entrez Gene)
Chr25 O13034 (UniProt | EBI)
NM_131385 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory